1905 movie network news Recently, the new film UGLYDOLLS, which was filmed by kelly asbury and co-director, exposed the posters of the characters. On the poster, this group of ugly and ugly little dolls made an incomparable appearance, which was very interesting.

Warm color matching, cute modeling, and cute movements all make people laugh. At present, the plot of the film has not been revealed, except that it is an animated film, mainly for the whole family, teenagers and women around the age of 20. This Chinese name will be used in movies, dramas and derivatives, please measure it comprehensively. As the first part of the series, this film tells the story of a group of dolls with strange looks. In order to pursue their dreams, they go to the perfect world and prove that they can achieve their wishes by being brave and true, and they are loved by people.

Uglydoll’s idea originated from two lovers of new york Art Institute. After the September 11th incident, Kim Sang-min from South Korea had to return to South Korea, and David Howens, who was far away in new york, missed him. So David Howens began to write to Kim Sang Min. In the letter, I will draw a little monster named Wage to amuse my girlfriend. Wage is an orange monster who wears an apron and works hard. One Christmas, Jin Sangmin sewed Wage into a doll and called it "Uglydoll", so the first Uglydoll was born. In the following years, Uglydoll has gradually developed into a big family, and has its own original cartoons, short films and puppets.

At present, the film is scheduled to be released on May 10, 2019, and the trailer will be released this week.

　　　　According to the website data of the Chinese Embassy in the DPRK, from 2002 to now, the number of China students studying in the DPRK has exceeded 1,700. Every year, 60 foreign students exchange scholarships between China and North Korea, and 70 foreign students at their own expense, all of whom are language students. Most people who study in North Korea come from the northeast of China, but there are also many students from Guangdong, Hunan and Henan provinces. Besides China students, there are also many Russians studying in North Korea. In addition, there are students from Laos, Cambodia and Mongolia. In addition, some people from western countries such as France and Canada also study here.

　　　　Do not take TOEFL GRE　

　　　　Only accept "double admission"

　　　　If you want to study abroad, you must first find someone who is familiar with Koreans to help you introduce and handle it. The application process is very simple. First, declare your name, and then go to the embassy in China to take the exam, answer the English paper, and have difficulty in high school. You don’t have to apply for IELTS, TOEFL and other grades. After passing, you have to study for one year in the preparatory course and four years in the undergraduate course. The preparatory course is not difficult, which is equivalent to the ESL course of studying in the United States, that is, passing the language barrier of Korean.

　　　　The only schools in North Korea that accept international students are Kim Il Sung University and kim hyong jik university of education, both of which are the highest institutions of learning in North Korea, and Kim Il Sung University is the cradle of North Korean politics. There are also some key institutions such as Jince Industrial University and Jin Yuanjun Music University in Pyongyang, but they do not accept international students.

　　　　Compared with most countries studying abroad, the tuition fees for studying in North Korea are cheaper. The annual tuition fee is about $7,000, including accommodation and tuition, excluding extra expenses such as travel. The school will organize international students to travel during the Chinese New Year holiday. But it can’t compare with North Korean students, because they go to college for free. School supplies, textbooks, school uniforms, accommodation fees and even local transportation fees are all paid in the form of scholarships.

　　　　Every year, the National Scholarship Fund Committee of China will also organize some public students to study in the DPRK in several schools for one semester. Students studying in the DPRK are not allowed to work or take part-time jobs, whether on or off campus. There is no so-called OPT after graduation, so you can’t find a job by yourself. North Korea’s visas are not as detailed as those in the United States. If international students want to stay after graduation, they must have an inviting unit.

　　　　"Jin Da’s students are very enthusiastic."　

　　　　Chinese is optional in foreign language classes.

　　　　Kim Il Sung Comprehensive University and kim hyong jik university of education, the former is the best comprehensive university in North Korea, which is equivalent to Peking University’s position in China. It is worth mentioning that the current CPC The Politburo Standing Committee (PSC) Zhang Dejiang graduated here. No matter from the campus environment, teachers and hardware facilities, it can be seen that North Korea has made great efforts in elite education in universities.

　　　　Liu Juan was an international student who went to North Korea in 2004. There were more than 20 Chinese students in that session. As public students organized by the state, they were treated as state guests in North Korea. Liu Juan told the reporter of Studying Abroad: "We got a national scholarship at that time, so we don’t have to pay tuition fees. Not only that, the state and the North Korean government will give us living expenses on a regular basis."

　　　　After arriving at the North Korean school, the school will arrange for North Korean college students to live with international students. These North Korean college students take a special bus to school with international students every day, eat together, participate in North Korean activities together, and go to various dormitories at night to ask if you have any problems in your study or life. "We usually ask them what they don’t understand, and they are all enthusiastic to answer. In fact, there are girls among them who are younger than us, but they always care about us like big sisters. So everyone gets along very happily in life. " Liu Juan told Study Abroad? Who.

　　　　Every morning, they always stand in front of the bus in neat clothes and carrying hand-held schoolbags, waiting for all of us to arrive before getting on the bus. Pedestrians reading while walking can often be seen on the streets of North Korea. "Koreans love reading and studying, especially college students." Liu Juan said, "On the way to school, roommates will also spend more than 20 minutes reading notes on subjects that need to be memorized, such as English, Chinese and Kim Jong Il’s guiding ideology. North Korea’s books and materials are poor, and some of the materials that college students read have been turned over, or they have copied the whole article by hand. "

　　　　Korean students can choose English or Chinese as their foreign language courses. In fact, basically they all know some Chinese, but it’s just a matter of level. Their class is similar to our junior high school class. Each student has a set of desks and chairs and sits upright in their respective seats. As soon as the teacher entered the classroom, everyone stood up and bowed to the teacher to say hello, and then began to teach. There will be no freedom and activity in the class that we always think in the college class, but it seems to be a little more serious and rigorous.

　　　　Labor is a compulsory course for all North Koreans, and college students are no exception. Every morning, when the bus enters the campus, we can always see college students cleaning roads and playgrounds with brooms and dustpans. Such a scene is not common in today’s China University campus. In addition to flowers and plants, there are some edible vegetables on campus. It is said that the school also feeds pigs and poultry in the backyard for the canteen.

　　　　Taking photos in the dormitory can play LOL and watch Korean dramas.

　　　　The treatment of international students in North Korea is good. Liu Juan, who is studying in North Korea, lives in a single room with two rooms and one living room. Carpets are laid indoors, with geothermal energy in winter and fans in summer. Each person is equipped with a single bed, desk and wardrobe, and some rooms are also equipped with televisions and bookcases. Configuration is really complete, more spacious than the dormitory of domestic universities, with public toilets and bathrooms. There is also a public kitchen in the dormitory. You need to buy an induction cooker, refrigerator and microwave oven for cooking. Usually, girls prefer cooking.

　　　　How to surf the Internet in North Korea is also a problem for international students. Not every room in the dormitory has internet, only fixed rooms have it. You can pull your own network cable and buy it together, but it costs $300/month and the price is higher. North Korea prohibits the use of Wi-Fi, and if it is found that it is secretly used, it will be fined.

　　　　The network used by overseas students is different from that used by Koreans. The network commonly used by ordinary people in North Korea is a domestic local area network covering all provinces, cities and counties in North Korea, but it is not connected to the Internet. The scope of international students will be broader, provided that VPN is available. After opening, LOL can also play, Korean dramas can also be watched, and Hollywood blockbusters can also be downloaded. But if you don’t open it, even Baidu can’t open it.

　　　　Some international students use Apple mobile phones, and the teacher must guarantee to sign the card. Many international students use Apple mobile phones and China brand mobile phones. Since 2013, North Korea has allowed foreigners to access the Internet through 3G networks. The monthly fee for accessing the Internet by mobile phone is about US$ 14, and 50M traffic is provided free of charge every month. The excess is charged according to the standard of RMB per megabyte in 1 yuan.

　　　　Usually, "I often call the water"

　　　　However, living in North Korea certainly has many unspeakable sufferings. For example, there are some obstacles to the basic needs of life such as toilets, bathing, making phone calls, running water and power supply. Liu Juan said: "It may be because the DPRK attaches importance to the living conditions of China students. In our dormitory, power outages are not common, but sometimes we are caught off guard, but we will call again soon."

　　　　Unlike every household in China which has a water heater, Korean people can take a hot bath at any time. Although there is a bathroom in the dormitory where foreign students live, hot water is not available all the time. Sometimes, if you want to take a comfortable hot bath, you have to go to a special public bathhouse. For example, for the international students of Kim Dae, the school will organize international students to take a bus to a bathhouse called Cangguangyuan once a week. Usually, if you want to wash it, you have to pay for it in the bathhouse, usually 2 dollars at a time. Zhang Wei, who is studying at Kim Il Sung University, told the reporter of Studying Abroad that North Korea will stop water from time to time, so the bathroom in each room is equipped with a big bucket, which is usually filled with water for emergencies. The voltage in North Korea is not very stable. After all, it depends on hydropower. In other words, it is "often called by water". Basically, everyone will buy a voltage regulator. If you don’t buy it, the service life of computers and mobile phones will not be too long.

　　　　The school is solely responsible for the diet of international students in North Korea, and every meal is provided free of charge by the school canteen. Liu Juan told the reporter of Studying Abroad that the quality of the meals provided by the school is very good. Apart from Korean food, the canteen occasionally cooks Chinese food, and every meal is also equipped with fruit. As we all know, many fruits in North Korea are imported from other countries. From the diet of international students, it can be seen that North Korea gives high treatment to international students.

　　　　"Made in China" daily necessities are expensive

　　　　Every time an international student goes to a new environment, he needs to go to the local area to buy daily necessities. Regarding the "shopping" experience in North Korea, Liu Juan told the reporter of Studying Abroad: "We need to buy a lot of daily necessities and food in Beisai. There is no large-scale department store in Beisai, but basic daily necessities can be found here. We just need to patiently look for them one by one."

　　　　Most of them need to be bought in foreign currency, and the price is not cheap. A box of 900ml milk made in Singapore is priced at $2.50; Oreo cookies cost $5; The asking price of Chinese-made Want Want Snow Cake is US$ 2, most of which are imported, with Singapore, Malaysia, China and Japan as the main import destinations. When you first arrive in North Korea, you need to buy a lot of daily necessities. There are Xicheng Market and Peony Market nearby, where you can buy fruits, vegetables and other daily necessities.

　　　　Through the gate marked with four characters of Xicheng Market, there are several residential buildings side by side on the right hand side, and there are five doors on the left hand side, four of which are entrances to four different areas of the market. From the outside to the inside, there are parking lots, grocery areas, building materials areas, industrial products areas and food areas.

　　　　Most of each booth is as big as a desk for primary school students, and it is filled with all kinds of goods waiting to be sold. The quantity of each commodity is small, mostly made in China, but the price is more than twice as high as that in China.

　　　　For example, a roll of ordinary transparent adhesive ranging from 50 cents to 1.50 yuan costs 800 yuan, equivalent to RMB in 8 yuan. 18 yuan’s small rechargeable desk lamp with RMB around costs 3,600, which is twice as expensive. There are countless such examples. Especially after entering the food area, this feeling will be more profound.

　　　　The basic structure of each area is basically similar, but the types of goods sold are different. The groceries area mainly sells clothes, shampoos, clothes hangers, headropes and other miscellaneous daily necessities. The building materials area sells such items as nails, tape, ropes, bicycle bells, screens and so on, and the number of male salespeople is much higher than that in other areas.

　　　　"I still enjoyed the experience of studying in North Korea this time."

　　　　Restaurants and shops in Beisai Commercial Street have been "found out" by Liu Juan and others. Which chicken leg is delicious, which kimchi fried rice is delicious, which one can easily change money, and which one is the most affordable to eat meat or vegetables … is one of the main topics they usually discuss.

　　　　Several restaurants frequented by international students are Liming Restaurant, Mingxing Restaurant and Ethnic Restaurant, and there is also a Korean currency restaurant called Kaixuan (paying in Korean currency). Although their menus are similar, the tastes need to be patiently distinguished to find the one that suits your taste best. Tasting Korean food has greatly enriched the extracurricular life of international students.　

　　　　In Liu Juan’s own words, although studying abroad didn’t make her experience the real life of the Korean people, it played a great role in her understanding of the country’s living habits and customs. "Studying abroad is to experience the cultures and habits of different countries and nationalities. I still enjoy the experience of studying in North Korea this time." Liu Juan told the reporter of Studying Abroad.

The "Good Bad Review" option is juxtaposed with "Online Application, Online Appointment, Online Consultation" and so on.

The evaluation level of "good bad review" is divided into five.

On October 28th, Wang Yi, a lawyer assistant in a law firm in Chengdu, opened a web browser, entered the keyword "Sichuan Government Service Network", entered the home page, found the online service window she needed in the "Personal Service-Professional Qualification" option, and immediately completed an application.

After some operation, Wang Yi’s working experience was excellent. She chose the smiling face pattern in the column of "Good Bad Review" to draw a satisfactory conclusion for this online work.

Wang Yi is an early adopter who holds a "power bar" with good and bad reviews. On the same day, Sichuan launched the "Good Bad Review" platform for government services. In the future, every user can play "good review" or "bad review" for the experience of government services like Wang Yi.

All service matters are included in the evaluation scope.

"This is an all-round revision." The person in charge of the relevant departments of the general office of the provincial government summed it up. He introduced, "The upgraded Sichuan government service network integrates seven major sections, such as’ home page, personal service, corporate service, direct access to cities and states, direct access to departments, interaction between the government and the people, and openness of government affairs’, and realizes five services, such as’ event service, identity authentication, payment service, license service and good and bad reviews’."

Among them, the new "good bad review" platform has attracted much attention. The person in charge said that in order to implement the requirement of establishing a "good bad review" system for government services in Premier Li Keqiang’s "Government Work Report" in 2019, Sichuan has specially issued a "Work Plan on Establishing a" good bad review "system for government services" in light of the actual situation, and formulated an overall "good bad review" action plan for the whole province. "The government service network has a’ good bad review’ area, which means that users can make an outspoken evaluation of the satisfaction of government services like online shopping. Whether it is praise or spit, or make comments and suggestions. "

On the network platform of "Sichuan Provincial Government Service Network", we can see that the administrative license, administrative payment, administrative confirmation, administrative ruling, administrative reward, and the handling of the people on the 12345 hotline have all been included in the evaluation scope of "good and bad reviews". The options of "Good Bad Review" and "Online Application", "Online Appointment" and "Online Consultation" are listed in the service options column.

Full coverage of online and offline "good bad reviews"

In the eyes of the experiencer Wang Yi, the construction of the platform of "good bad reviews" is to actually hand over the "assessor" to test whether the client is satisfied. "What is the experience of the parties, and they have the most say."

According to the design, the evaluation level of "good bad reviews" is divided into five levels, namely, very satisfied, satisfied, basically satisfied, dissatisfied and very dissatisfied. Evaluation to take real-name registration system, enterprises and the masses every time for a government service matters, can be evaluated after the completion of a ..

According to the person in charge of the platform, it is a prominent feature of the platform to achieve full coverage of online and offline "good and bad reviews" channels. Among them, online evaluations include Sichuan government service network, Tianfu Tongban, WeChat applet, Alipay applet, etc. Offline evaluation includes evaluator, code scanning, SMS, self-service terminal, QR code, "12345" government service hotline, etc.

Take the online evaluation of Sichuan government affairs service network as an example. When the clerk wants to evaluate the completed documents, he can enter the user center, select "My Evaluation" and click "Documents to be evaluated" to evaluate the listed items. It is worth mentioning that the service object is not evaluated within 7 working days after receiving the service, and the system will evaluate it as "basically satisfied" by default.

"Bad review" object completes rectification within 15 days.

What’s the use after obtaining the evaluation results? The person in charge of the relevant departments of the general office of the provincial government responded that the "good bad review" platform aims to improve the quality of government services in the province and accelerate the creation of a market-oriented and legalized international business environment. If the "dissatisfied" or "very dissatisfied" evaluation items are found to be true, it is required to make rectification within 15 days, and the rectification results will be fed back to the evaluator through online government service platform, mobile user center and SMS.

For the incentive of "praise", it is clearly put forward that all relevant departments (units) in all parts of the province should link "praise" with the performance appraisal of units and individuals as an important content of target performance, annual assessment and advanced selection, and obviously increase the praise and incentive. (Reporter   Li Yuanli)

Beijing, December 6 (Xinhua) The biggest highlight of this year’s medical insurance negotiations is the suspense brought by the participation of more than 20 domestic innovative drugs in the negotiations.

On December 3, the new medical insurance catalogue of the National Medical Insurance Bureau was officially released. Rongchang Bio, which promoted two "world-class domestic innovative drugs" independently developed at one time to the medical insurance catalogue, immediately became the focus.

Taita Xipu (trade name: Taiai? ), vidiximab (trade name: Aidixi? ) was conditionally approved for listing by National Medical Products Administration (NMPA) in March and June, 2021 respectively. The former is the world’s first "dual-target" biological new drug for the treatment of systemic lupus erythematosus, and the latter is the first original antibody-coupled (ADC) drug in China. It is these two innovative drugs that have been approved to enter the medical insurance catalogue this time.

In less than half a year, two world-class original new drugs have been approved for listing; Just a few months later, two new drugs entered the medical insurance catalogue at the same time. Rongchang Bio’s innovation ability, product quality and commercialization speed are once again presented.

China’s self-developed world-class new drug "quickly" reduced the price into medical insurance

Why do innovative drugs get attention when they enter the medical insurance catalogue? Because this means the opening of a new life channel for patients with corresponding indications. Pay a lower fee, use the world’s leading new drugs and good drugs, and stay away from "poor diseases".

In fact, according to preliminary estimates, the adjustment of the national medical insurance drug list in the past three years, compared with the pre-negotiation market price, has reduced the burden on patients by nearly 170 billion yuan and benefited 100 million patients through negotiation price reduction and medical insurance reimbursement.

"The two pioneering new drugs, Taitacip and Vidicotuzumab, are quickly reduced in price into medical insurance, which can improve the accessibility of these two world-class biological new drugs in the country, help China’s over one million patients with systemic lupus erythematosus and the vast number of patients with gastric cancer to get effective treatment, reduce the economic burden of patients and their families, and better play the social benefits of drugs." Dr. Fang Jianmin, CEO and chief scientific officer of Rongchang Bio, said.

Systemic lupus erythematosus patients and other first domestic innovative drugs.

Systemic Lupus Erythematosus (SLE) is a lifelong systemic immune disease, which can cause damage to kidneys, cardiovascular system, lungs, digestive system, blood system, blood vessels, eyes and other organs and tissues, and significantly increase the risk of death of patients. Its harm makes people talk about it. According to "Guidelines for Diagnosis and Treatment of Systemic Lupus Erythematosus in China in 2020", there are more than 1 million patients with systemic lupus erythematosus in Chinese mainland, and the prevalence rate is the second highest in the world.

However, for a long time, a large group of patients have been faced with the dilemma of drug use-traditional glucocorticoids, immunosuppressants, etc. are often accompanied by great toxic and side effects, which are unbearable for patients. At the same time, it is difficult to "breed" new therapeutic drugs. In the past 60 years, the US Food and Drug Administration (FDA) only approved a drug for the treatment of systemic lupus erythematosus in 2011 (Berizumab developed by GlaxoSmithKline).

Rongchang Bio was included in the national medical insurance drug list this time, which is tetasip for injection (specification: 80mg/ piece). It is the first innovative drug approved in the treatment of systemic lupus erythematosus in China, and it is also the first-in-class biological drug in the world.

Different from the single-target design of listed drugs, the "double-target" design of Tatasip can inhibit BLyS and APRIL, two key factors that make B lymphocytes differentiate and mature at the same time, which can reduce the immune response of the body more effectively and play a "two-pronged" effect on treatment. The key clinical data showed that the systemic lupus erythematosus response index (SRI) in the high-dose group was significantly higher than that in the placebo control group (79.2% vs 32.0%) after 48 weeks of treatment, and the improvement of SRI was significantly better than that of the new biological drugs currently on the market. At the same time, the macromolecular drug Tetasip can be metabolized directly through cells, instead of liver and kidney metabolism, which can significantly reduce the side effects of traditional drugs and has higher safety. In a word, as a new drug with new target, new structure and new mechanism, Tetasip brings infinite new hope to the global SLE medical field.

(Photo courtesy of the enterprise, issued by Yangguang. com)

Professor Zhang Fengchun, the head of clinical trial of Taitacip and the chief physician of Peking Union Medical College Hospital, said: "Compared with the existing treatment methods, the main therapeutic indexes of Taitacip have been greatly improved, which is a major breakthrough in the treatment of systemic lupus erythematosus, marking that China has taken the lead in the field of research and development of new drugs for the treatment of systemic lupus erythematosus. The inclusion of this drug in the national medical insurance drug list will further improve the accessibility of drugs, greatly reduce the medical burden of patients with systemic lupus erythematosus, and bring them higher quality survival benefits. "

Tetasip’s innovation has been recognized internationally, and its invention patents have been authorized by China, the United States, Europe and other countries and regions. Besides the indications of systemic lupus erythematosus, domestic and international clinical trials of Tatasip for neuromyelitis optica spectrum diseases, rheumatoid arthritis, IgA nephropathy, Sjogren’s syndrome, multiple sclerosis and myasthenia gravis are being conducted in an orderly manner.

To fill the blank of back-line therapy for gastric cancer patients with HER2 overexpression in China.

Another new drug of Rongchang Bio, which is included in the medical insurance catalogue, is vidiximab for injection (specification: 60mg/ piece), which is approved for patients with locally advanced or metastatic gastric cancer (including adenocarcinoma of gastroesophageal junction) who have received at least two systemic chemotherapy (HER2 immunohistochemical results are 2+ or 3+).

In China, gastric cancer is the second largest cancer species after lung cancer, with an annual incidence of 400,000, ranking first in the world. The morbidity and mortality are both high. 80% of patients with gastric cancer in China were in advanced stage when they were diagnosed. For most patients with advanced gastric cancer, chemotherapy is still the first choice for first-line treatment in the past few decades. However, the therapeutic effect of chemotherapy is limited, and the side effects are great, and the precise drugs for patients with gastric cancer who overexpress HER2 are even blank.

According to the latest data, the objective remission rate (ORR), disease control rate (DCR), median progression-free survival (PFS) and median overall survival (OS) of patients with HER2 overexpression gastric cancer treated with vidicon were 24.8%, 42.4%, 4.1 months and 7.9 months, respectively, which showed higher efficacy and better safety.
Therefore, China’s first original antibody-coupled (ADC) drug, vidiximab, developed by Rongchang Bio, went on the market, which filled the blank of back-line treatment for patients with gastric cancer whose HER2 was overexpressed in China.

As an ADC drug, vidiximab has the characteristics of antibody targeting and small molecule drug killing, and can accurately identify and kill tumor cells by targeting HER2 protein on the tumor surface. It has achieved world-leading clinical data in clinical trials for treating gastric cancer, urothelial cancer, breast cancer and other tumors.

Professor Shen Lin, vice president of Peking University Cancer Hospital, director of the Department of Gastroenterology and Oncology, and deputy director of Beijing Institute of Cancer Prevention and Treatment, said: "When vidiximab is featured by a wider range of treatment beneficiaries, a more balanced curative effect, safe benefits and a more economical and convenient detection process, and it has made revolutionary progress in the history of anti-HER2 treatment for gastric cancer, it is also inevitable that it will be highly recognized by National Medical Products Administration and the National Medical Insurance Bureau."

At the press conference on the adjustment of the national medical insurance drug list in 2021, Professor Shi Yuankai of the Cancer Hospital of China Academy of Medical Sciences mentioned that vidiximab is the first original antibody-coupled drug in China, and it has achieved good results in tumors such as gastric cancer and breast cancer. It is effective not only for patients with overexpression of human epidermal growth factor receptor -2(HER-2), but also for patients with low expression of HER-2. This time, the price of vidiximab was successfully reduced and entered the medical insurance, which benefited more cancer patients and filled the gap in the guarantee. While improving the drug guarantee for gastric cancer to the international mainstream drug use level, the burden on patients was greatly reduced.

Like Tatasip in the treatment of systemic lupus erythematosus, Videcituzumab is highly recognized internationally: this new drug is the first ADC drug in China that has been recognized as a breakthrough therapy by both FDA of the United States and NMPA of China. In August, 2021, Seattle Gene, an internationally renowned biopharmaceutical company, obtained the global (except Asia-Pacific) exclusive license agreement for vidicon with a down payment of up to US$ 2.6 billion and milestone payment, and a gradient sales commission of more than 15%. The transaction volume set a new record for overseas authorization of a single product of China pharmaceutical companies.

Innovative drugs are included in medical insurance, and the volume will obviously drive more innovations.

The medical reform in China continues to deepen, and the time for innovative drugs to be included in medical insurance has been greatly shortened.

The Blue Book on the Progress and Effectiveness of Medical Insurance Drug Management Reform shows that among the 34 innovative drugs listed from 2016 to 2020, 26 drugs have been included in the medical insurance catalogue, accounting for 76.5%. At the same time, in 2017, the time required for new drugs from listing to inclusion in medical insurance will be shortened to 1-8 years in 2019 and further reduced to 0.5-5 years in 2020.

The speed at which Rongchang Bio’s two innovative drugs entered the medical insurance is also a proper "top student". The characteristics of the two innovative drugs, such as "initiative", remarkable clinical effect, better safety and huge patient group, all escort their rapid inclusion in the medical insurance catalogue.

As for the new drugs with good curative effect, strong innovation and large clinical demand, it can quickly expand the sales channels and greatly increase the sales and market share of new drugs in a short time.

For example, according to the Blue Book on the Progress and Effectiveness of Medical Insurance Drug Management Reform, the dosage and amount of 17 kinds of anticancer drugs successfully negotiated in 2018 increased by 25.8 times and 8.8 times in the first quarter of 2021 compared with the first quarter before the negotiation (the third quarter of 2018); In the first quarter of 2021, compared with the first quarter before the negotiation (the fourth quarter of 2019), the amount of drugs successfully negotiated in 2019 increased by 10.4 times and the amount increased by 2.7 times.

Rongchang Bio-Tatasip and Vidicotuzumab are aimed at "a wide range of clinical unmet needs". With the opportunity of entering the medical insurance drug list, these two heavy new drugs may achieve rapid volume increase and gain more market share and economic benefits. And these will eventually lead to more innovations.

With the continuous introduction of policies to encourage innovation, such as accelerating the review of new drugs and normalizing medical insurance negotiations, enterprises that focus on early accumulation, do not blindly follow the trend of project establishment, and closely focus on how to solve the actual clinical needs are bound to stand out.

Rongchang biology is one of them.

Rongchang Bio, founded in 2008, has been focusing on the discovery, development and commercialization of antibody drugs such as antibody drug conjugate (ADC), antibody fusion protein, monoclonal antibody and bispecific antibody. At present, Rongchang Bio has developed more than 20 candidate biopharmaceutical products, and more than 20 indications of 7 products are undergoing clinical trials or have entered the commercialization stage.

In the best era of the development of innovative pharmaceutical companies, inclusion in the medical insurance catalogue has just begun for Rongchang creatures with outstanding research and development capabilities and rich reserves.

CT showed that Ms. Li’s thumb was injured.

　　On November 23, Ms. Li, who lives in Jilin City, Jilin Province, turned to the cover news cloud for help. On November 20, when she used the "Flower Pig Taxi" (hereinafter referred to as Flower Pig) network car platform to take a taxi, her right thumb fingernail fell off because of the driver’s operation error. Three days have passed, but no one has come out to take responsibility.

　　"I have spent more than 2000 yuan to see a doctor. Looking for a driver for this matter, the driver ignored me; Looking for a platform, the platform said they had no choice; Call the police. The police said it was a civil dispute. I really don’t know what to do. " Ms. Li said.

　　The driver stepped on the accelerator.

　　The passenger suffered a heart-rending pain.

　　Ms. Li introduced that on the evening of November 20th, she and her boyfriend took a taxi from Songhua River New Town in Jilin City to the west gate of Yulong Bay. After arriving at the destination, she got off with her boyfriend. However, when they had not completely closed the door, the driver had already started the car and left. "He should be in a hurry to catch the next order, because when he was about one kilometer away from the destination, the driver ended our order ahead of schedule, saying that he would take the next order in advance."

　　Ms. Li said that she felt heartbreaking pain at the moment when the car left. "At that time, the thumb of my right hand was caught by the door, and his speed was relatively fast, which caused the nail cover of my thumb to be torn off." Ms. Li said that at that time, her fingers were bloody, and she squatted on the ground in pain, and the driver didn’t know whether he didn’t find it or deliberately ignored it, so he drove away.

　　Nobody takes responsibility.

　　Civil disputes cannot be filed by the police.

　　Later, Ms. Li and her boyfriend called their friends who lived nearby and asked them to drive them to the hospital. When I arrived at the hospital, I found that Ms. Li had an open fracture of her thumb and had to undergo surgery. "I thought it was just an ordinary trauma, but I didn’t know it was bad until I heard the operation. In order to save the cost of surgery, I changed three hospitals in a row before I found a slightly cheaper one. "

　　After the operation, Ms. Li found the driver at that time. The other party said that if she had the responsibility, she hoped that Ms. Li would find herself through the police. After Ms. Li called the police, the police told her that the matter was a civil dispute and could not be filed. In desperation, Ms. Li had to pin her hopes on the car platform of Hua Xiaozhu. "At that time, I thought that the car was found from them and they should manage it." However, I didn’t expect that the flower pig platform said that the platform and the driver only belong to the cooperative relationship, and I hope that Ms. Li will take legal procedures to solve the problem.

　　Ms. Li said that she learned about the car platform of Flower Pig Network from a friend a few days ago, and only used it five or six times until the day of the accident. "At that time, I heard that the after-sales customer service here was not very good, but I thought it was cheap, so I didn’t think so much. I didn’t expect it to be so troublesome after the accident." Ms. Li said that at present, she hopes that the car platform of Flower Pig Network can give herself a statement, "I have been playing the piano since I was a child, and now this problem has arisen. I don’t know if I can still play the piano."

　　Flower pig platform response

　　Customer service has been involved in this matter.

　　On the afternoon of November 23, Huaxi Dushi Bao and the cover journalist contacted the Flower Pig Platform. The other party said that there is a special customer service involved in this matter, which is not what Ms. Li said. "We also contacted the driver. The driver also said that if the investigation is clear that it is indeed his responsibility, he is willing to take responsibility. I hope Ms. Li can give us some time to investigate. "

　　The other party also said, "We have made preliminary communication with passengers and drivers, and we will tell passengers about the follow-up treatment and progress at the first time."

　　CCTV News:The State Council held a press conference on the 16th. Zhao Zhiguo, spokesperson of the Ministry of Industry and Information Technology and director of the Information and Communication Administration, said that the Ministry of Industry and Information Technology attached great importance to the protection of the rights and interests of APP users. In recent years, comprehensive measures have been taken to continuously improve the governance system. The related work has been promoted from four aspects, and new progress and results have been achieved.

　　First, we will continue to carry out rectification actions that APP infringes on users’ rights and interests. Organized the communications administrations of eight provinces (cities, districts) in Guangdong, Zhejiang, Jiangsu, Shanghai, Tianjin, Sichuan, Anhui and Inner Mongolia, carried out six batches of centralized sampling inspection, inspected 760,000 apps, notified 748 illegal apps, and removed 245 apps that refused to rectify, and continued to maintain a high-pressure shock to violations.

　　The second is to strengthen the supervision of key responsibility chains. Establish an application store ranking notification mechanism where the main responsibility is not implemented, and urge application stores to strengthen self-inspection and clean-up, remove the problematic apps, and carry out the review of new apps. By the end of May this year, the number of apps nationwide was 3.02 million, which was 13% lower than the 3.5 million apps before the Ministry launched special rectification. Through the adjustment of quantity and the removal of illegal apps, the quality of apps is optimized, so that compliant apps can develop healthily. At the same time, the discovery rate of APP sampling problems in the app store has steadily declined.

　　The third is to carry out special rectification of the problem of APP pop-up harassing users. Focus on two problems: it is difficult to close the information of open screen pop-up window that strongly reflects to users and using pop-up window to mislead users to click and jump to carry out special rectification. The masses’ reactions to these two problems are relatively concentrated. One is that they can’t be shut down, and the other is to mislead users to jump. According to statistics, in the second quarter, the number of complaints about APP pop-up information decreased by 50% from the previous month; Among the top 100 APP applications in terms of user usage, the discovery rate of the problem that it is difficult to close the screen information dropped from 69% to 1%. It turned out that the number of apps that found such problems was relatively large, but now it is getting less and less. The discovery rate of misleading users to click and jump by using pop-ups dropped from 90% to 12%.

　　The fourth is to vigorously improve the technical testing capability. Using big data, artificial intelligence and other technologies, we will continuously improve the automatic detection ability, monitoring ability and data analysis ability of the national APP technology detection platform. At present, the platform has the ability to detect 150,000 apps per month, and the detection coverage will reach 1.8 million apps before the end of the year.

　　In the next step, the Ministry of Industry and Information Technology regards APP governance as a concrete measure of "I do practical things for the masses", and strengthens its work from three aspects, with constant momentum and constant pace, and strives to create a safer, healthier and cleaner APP application environment for the broad masses of the people.

　　The first is to promote the improvement of management policies and industry standards. On the basis of fully absorbing the opinions from all walks of life, we will jointly issue and implement the Interim Provisions on the Protection and Management of Personal Information of Mobile Internet Applications with relevant departments. The previous paragraph of this Regulation was publicly solicited for opinions on the Internet, and all walks of life put forward some good opinions and suggestions, which we are studying and adopting. On this basis, it will be promulgated and implemented in conjunction with relevant departments as soon as possible. At the same time, it also organizes the formulation and improvement of relevant industry testing standards to provide more solid policies and standards for APP governance.

　　The second is to organize and carry out service perception improvement actions. Focus on some key links of users’ poor perception and experience of APP service, organize and carry out service perception improvement actions, and take effective measures to further promote the improvement of APP service quality. We plan to launch the "Service Perception Promotion Action" in the second half of the year, starting from the perspective of user service perception, to improve the governance strength and governance effect.

　　The third is to organize the issue of "looking back". On the basis of normal supervision, we will carry out a "look back" on key issues and key enterprises in a timely manner, and increase penalties for enterprises that repeatedly violate the rules to call the address book and the geographical location authority of users, so as to ensure that the rectified problems "do not rebound or repeat".

　　According to the "Humanities Meilong" WeChat WeChat official account news, the epidemic prevention and control headquarters of COVID-19 in Meilong Town issued the "Letter to Meilong Residents".

Residents and friends:

　　On August 15th, a new asymptomatic infected person was found in Meilong Town. During the isolation control, it was found that the residential address was No.1870, Xinzhu Road, and measures such as terminal disinfection had been implemented.

　　According to the current epidemic situation and the national and municipal epidemic prevention and control requirements, in order to find and control the epidemic risk as soon as possible, the town will continue to carry out the whole town’s nucleic acid screening on August 16th (Tuesday), August 18th (Thursday) and August 21st (the high school risk areas will be arranged separately).

　　1. Sampling time of concentrated nucleic acid in Jucun: 17:00-22:00 on the same day. The sampling period shall be closed for management, and it shall be unblocked after the sampling. Specifically, the notice of the village where you live shall prevail.

　　2. Employees of merchants, enterprises and institutions along the street can participate in nucleic acid sampling at the nearest place during the normal working hours.

　　On August 17th (Wednesday), 19th (Friday) and 22nd (Monday), residents went in and out of Jucun on the basis of the previous day’s nucleic acid sampling records, and employees of merchants, enterprises and institutions along the street went to their posts and went in and out of their units on the basis of the previous day’s nucleic acid sampling records.

　　Please actively support and cooperate with the residents, remind and urge each other to ensure that no one is left behind or missed.

　　Tips

　　1 About preparation in advance

　　Please click on the "Nucleic Acid Code" function on the homepage of the "With the Bid" APP, the "With the Bid" WeChat applet or Alipay applet in advance to generate a "Nucleic Acid Code" and take a screenshot to save the picture.

　　About the elderly and children

　　Click "Code with relatives" on the page of "Code with application" to apply for "nucleic acid code" for the elderly over 60 years old or minors under 18 years old. If you have previously applied for the "relatives’ application code", just click the "nucleic acid code" next to the relatives’ names to get the "nucleic acid code" of the relatives.

　　3 About "Offline Code"

　　The nucleic acid code can be used offline, and it can be used repeatedly for the same application, with a validity period of 30 days. The "nucleic acid code" can also be printed out, which is convenient for the elderly and children at home to sample and register nucleic acid.

　　4 About "use whatever you can" and "never leave home"

　　Residents are requested to actively cooperate and participate in nucleic acid testing in a timely and orderly manner according to the notification requirements of communities or units.

　　5 About Yang Healing Personnel

　　Yangyu personnel will go to the community sampling point for "single person and single tube" sampling with the electronic or paper release list and nucleic acid code or with the bid for "green code".

　　6 About personal protection

　　The weather is hot, please pay attention to heatstroke prevention and cooling, and participate in nucleic acid sampling in batches and in an orderly manner. During the sampling period, wear a mask, keep the distance of "2 meters" and do personal protection.

　　7 About the result query

　　Residents can check the results of nucleic acid testing through "with the bid".

　　8 About consultation

　　If in doubt, you can consult your neighborhood Committee or village Committee.

　　Meilong town COVID-19 epidemic prevention and control headquarters

　　August 15, 2022

Cctv news(News Network): In combination with local characteristics, Longyan, Fujian Province has increased the cultivation of new formats such as online consumption and platform economy, raised the consumption level, and stimulated the new vitality of the old district economy.

At present, the live broadcast rooms of various agricultural products in Longyan are very lively. Peanuts, dried sweet potatoes and passion fruits have become the protagonists promoted by fruit farmers. Here, mobile phones have become "new farm tools" and live broadcasts have become new farm work.

Li Qiusong, the inheritor of Fujian time-honored Longyan’s "Shan Erzai" skillWe have many good products and time-honored brands in Longyan, which used to be known only by local people. Now, through e-commerce, we do live broadcast and bring goods, and promote these good things to the whole country. The sales volume has gone up at once, and sometimes it even exceeds the supply.

Longyan is rich in high-quality agricultural products with good quality and low price, but in the past, the channels were single and the sales were not smooth. In recent years, Longyan has adapted to local conditions, guided farmers and enterprises to change the traditional sales model, popularized speed-up network broadband, and trained e-commerce skilled personnel. In 2015, rural e-commerce in Longyan developed rapidly, covering all counties, townships and villages in the city. Today, Longyan has built 12 e-commerce industrial parks, with more than 36,000 e-commerce enterprises and nearly 40,000 direct employees. In the first half of this year, Longyan’s online retail sales reached 7.36 billion yuan, an increase of 71.7%.

According to the relevant requirements of the county government for epidemic prevention and control, during the epidemic prevention and control period, in order to facilitate the access management of people in our county community and family hospitals, and to facilitate the statistics and screening of data, from now on, our county will promote the use of "every village enjoys" scanning code registration in county communities and family hospitals.

The following small series will share with you the registration and use process of scanning codes for people in the community and their families.

In the first step, each community and family courtyard has its own two-dimensional code, and community residents use WeChat to scan the code when entering and leaving the community and family courtyard.

Step 2: After scanning the code, you can see that there are two options under the visitor registration. If you are going out of the community and your family’s hospital, please choose: Go out (daily going out, going out for work), if you are going into the community and your family’s hospital, please choose: Enter (daily entering, returning from abroad).

Step 3: Fill in the relevant information. When you fill in the information for the first time, you must fill in the relevant information carefully. As shown in the above figure, the information such as mobile phone number, ID number, name and residence number must be accurately filled in. When scanning the code for registration for the second time, just fill in the mobile phone number, and the ID number and name will be automatically displayed.

If it is a daily trip, such as going to work or shopping, choose other travel modes as shown in the above figure, and fill in the destination as work or shopping; If it is a daily entry, such as going out for shopping after work, where to fill in the off-duty or shopping, just choose another way to return.

What needs to be emphasized here is that when filling in the information, the temporary or returning personnel must fill in the relevant information truthfully. If they are migrant workers returning to school, the travel mode, destination, work unit or school must be clearly filled in; If it is a foreign returnee, the place of origin, the way of returning home and the current place of residence must be clearly filled in.

Finally, after the prevention and control personnel of the community and their families’ hospitals measure the temperature of the people entering and leaving, they can be released only after they have carefully filled in and submitted the information truthfully.

Tips: It is the key to win our county’s fight against the epidemic by guarding the gate of the residential area and the family members’ hospital. Please ask the residents of the residential area and the family members’ hospital to carefully cooperate with the prevention and control personnel to do a good job of scanning the code and fill in the relevant registration information truthfully. If you don’t understand the relevant operation, you can also ask the prevention and control personnel to assist in the registration. You can also register the paper entry and exit registration form because you don’t have your mobile phone, your mobile phone is dead, and you are not a smart phone. The prevention and control personnel in the community and their families’ hospitals must do a good job of on-site supervision. No matter how good the technical means are, they need to be implemented and controlled, especially the access control of non-staff members. They also need to check the pass information on site and strictly control the access times of the community and their families’ hospitals with access cards, so that all of us can do our best to prevent and control the epidemic, build a solid security barrier for the residents in the community and their families’ hospitals, and resolutely win this war without smoke.

Editor: Yang Liufeng

Original title: "Important Tips! Community and family members’ hospital personnel in and out of the scanning code registration process "

A blank house usually refers to the state that only the basic building structure construction is completed when the house is delivered, and the walls and floors are only preliminarily treated. For some people, due to various reasons, they will choose to live directly in a rough house. So how to adapt to this living condition, and what living methods and precautions are there?

In adapting to the living conditions of rough houses, we must first build basic living facilities. Because the rough house is not decorated, the water and electricity lines may only be reserved. To ensure the safety of electricity use, we can buy qualified patch panels and plan the use of electrical appliances reasonably to avoid tripping caused by using multiple high-power electrical appliances at the same time. In terms of water use, if the water pipes in the bathroom and kitchen have been connected, it is necessary to check whether there is water leakage, and at the same time, some simple storage containers can be prepared to store washing water.

Living in a rough house, keeping warm and insulating is also a problem that needs attention. The walls and roofs of rough houses are not insulated, which will be cold in winter and hot in summer. You can stick a thermal insulation film on the window, lay a thick carpet on the ground and hang some thick curtains on the wall to keep warm and insulate.

In terms of living methods, space utilization should be reasonable. The blank room is empty, so you can use simple furniture such as shelves and wardrobes to divide the space and separate the sleeping area, storage area and activity area. At the same time, attention should be paid to maintaining indoor ventilation, because the air circulation of rough houses may be poor, and long-term lack of ventilation will lead to indoor odor. You can always open the window and let the air convection.

Regarding matters needing attention, safety is the top priority. The floor of the rough house may be uneven, and there is a lot of construction waste, so it should be cleaned up in time to avoid tripping and injury. In addition, due to the lack of door and window locks, we should pay attention to the safety of property and lock the doors and windows as much as possible when going out. In terms of hygiene, because there is no decoration, dust is easy to accumulate, so it should be cleaned regularly to keep the room clean.

The following is a table about the comparison between rough housing and decorated housing:

In short, living in a blank room needs to be well prepared in all aspects, from the construction of living facilities to safety and hygiene, so as to have a relatively comfortable living experience in the blank room.

[Disclaimer] This article only represents the author’s own views and has nothing to do with Hexun. Hexun.com is neutral about the statements and opinions in this article, and does not provide any express or implied guarantee for the accuracy, reliability or completeness of the contents. Readers are requested for reference only, and please take full responsibility. Email: news_center@staff.hexun.com.