From "talking about the color change of tuberculosis" to "staying out of the area" in diagnosis and treatment, what has tuberculosis prevention and control experienced in the past 70 years?

  Cctv news(Reporter Zhang Ke Yi) Tuberculosis, commonly known as "consumption disease", is a chronic respiratory infectious disease caused by the invasion of mycobacterium tuberculosis into human body. Mycobacterium tuberculosis may invade all organs of human body, and tuberculosis is the most common one. As an ancient disease, tuberculosis can be traced back to the Neolithic Age. Scientists used modern detection technology to find mycobacterium tuberculosis in Egyptian mummies in 3000 BC.

  In A Dream of Red Mansions, one of Four Great Classical Novels’s well-known novels, Lin Daiyu, a sick beauty, actually got consumption. What is intriguing is that among the modern writers in China, there is a long list of those suffering from tuberculosis: Ba Jin, Qu Qiubai, Lu Xun, Yu Dafu, Ye Zi, Xiao Hong … … Tuberculosis is also involved in many of their literary works, such as Lu Xun’s short story Medicine, Yu Dafu’s Chi Guihua, Boundless Night, Ba Jin’s Home, Cold Night and so on. At that time, tuberculosis ranked first in the list of causes of death. "Ten diseases and nine tuberculosis" and "talk about tuberculosis" are not sensational.

  Nowadays, tuberculosis is still one of the top ten deadly diseases in the world. More than 1.6 million people die of tuberculosis every year in the world, and there are about 10 million new tuberculosis patients every year, with an incidence rate of 1.33/100,000. In China, the epidemic situation of tuberculosis is declining year by year. According to the data of 2018, there are 823,000 cases of tuberculosis patients reported in China, with a reported incidence rate of 59.3/100,000. However, it is worth noting that the severity of tuberculosis drug resistance in China is higher than the global average. How to do a good job in drug-resistant prevention and treatment of tuberculosis and accelerate the process of ending tuberculosis has become a major public health problem for the government, medical institutions and even the whole society.

  "Institute-linked remote diagnosis and treatment platform"

  Explore a new model of tuberculosis diagnosis and treatment

 

  Beijing tuberculosis therapy institute liandong remote consultation center 

  "Hello, Director Gao, I saw your number here today." On the morning of March 22, 2019, Xiao Zhang, a pulmonary tuberculosis patient who lives in Daxing District, Beijing, greeted Gao Mengqiu, the chief physician of Beijing Chest Hospital, 50 kilometers away, through the big screen at Daxing District Tuberculosis Control Center and started his visit. He also became the first online patient on the "hospital-linked remote diagnosis and treatment platform" for tuberculosis prevention and control in Beijing.

  "I have seen the film you shot yesterday. The lesion has been absorbed and recovered quite well. You have been taking medicine for more than 2 months now, and the infectivity is gone. But you should stick to taking medicine and you will be cured in about 9 months." On the screen, Gao Mengqiu gave Xiao Zhang treatment advice. "Drink milk every day, eat eggs, and sleep before 10 o’clock to ensure your resistance. Do you know that you get this disease because you usually don’t pay attention to rest and your resistance drops? "

  This remote diagnosis and treatment made Xiao Zhang excited. He admits that in the process of seeing a doctor, he once considered the examination in the local tuberculosis control center, but the concept of going to a big hospital drove him to choose the Beijing Chest Hospital in Tongzhou. "In fact, sometimes I understand that this is unnecessary, but I just feel that going to the top three hospitals is practical." He also said that he knew he shouldn’t go to public places, but in order to see a doctor, he had to squeeze the bus, take the subway and wear a mask, and he was afraid that others would treat him differently, so sometimes he didn’t bring it. He said: "But now, I can see the expert number of the top three hospitals at the CDC in front of my house, which is simply great."

  Guan Yongchun, director of Beijing Daxing District Institute for Tuberculosis Control and Prevention, said at the remote consultation site: "This model is a supplement to medical technology for us, which is more convenient for us to manage patients." Beijing Changping District Tuberculosis and Prevention Institute and Daxing District Tuberculosis and Prevention Institute became the first members of the "hospital-linked remote diagnosis and treatment platform". It is understood that after the "new model" is officially completed, all district and county clinics in Beijing will establish remote clinics with Beijing Chest Hospital to provide services to district and county patients through face-to-face online video.

  Li Liang, vice president of Beijing Chest Hospital and executive vice president of Beijing Tuberculosis Diagnosis and Treatment Technology Innovation Alliance, said: "The biggest change is to change the diagnosis and treatment of tuberculosis from patients seeking medical treatment everywhere to ’ Foot-out area ’ , the change of getting the high-quality service from the superior hospital at home; However, it has expanded the probability of infection from chariots and horses to the nearest place and reduced the spread; Referral from a number of hospitals, repeated medical treatment, timely detection and diagnosis, and timely standardization of treatment changes. "

  Peer education for patients with multidrug-resistant tuberculosis

  "I’m cured, so I decided to stay."

 

  Say "No" to Tuberculosis (Design: Liu Zhengqiang) 

  Xu Xinghua said: "All the medical staff who accompanied and cared for me all the way and ‘ 57 Heaven and Earth ’ My peers have asked me to stick to this job. Without them, I wouldn’t be here today. So when I was cured, I decided to stay. For the health of more patients, I am willing to be their ‘ Butler ’ 。” 

  One day in September 2013, Xu Xinghua went to a local hospital because of fever, cough and pain in his feet and joints. The doctor said that he had rheumatoid disease. After more than four months of treatment, Xu Xinghua was diagnosed with dermatomyositis. After treatment according to the doctor’s advice, he still had a fever repeatedly, once reaching 40 degrees, which lasted for another five months, and finally he was diagnosed with tuberculosis.

  "At that time, when my friends came to see me, I would say that I had rheumatism. I was afraid that my friends would stay away from me if they knew that I had tuberculosis." Xu Xinghua said that in addition to being afraid of losing friends, he also faces a heavy economic burden. Xu Xinghua’s family is in the countryside. Before that, some savings were spent by him, and he even borrowed a loan. He wanted to give up treatment.

  On July 1, 2014, Xu Xinghua was transferred to Yunnan Tuberculosis Clinical Treatment Center for hospitalization. During the treatment, the danger was constant. He had an extremely serious systemic rash. He was treated with second-line anti-tuberculosis drugs because of serious drug allergy. He suffered from liver failure for many times and complicated with bone tuberculosis. He was cured in October 2017 with the joint efforts of his family, patients and medical staff.

  "Illness can destroy my body, but it can’t destroy my will", which is the impression Xu Xinghua left for his patients. In 2015, Xu Xinghua joined the "57 Tiandi" peer team of Yunnan Tuberculosis Clinical Treatment Center, which is a tuberculosis consultation and exchange network platform managed by tuberculosis patients. He hopes to guide and encourage other patients to adhere to scientific treatment through his own experience.

  Due to the long course of treatment and many adverse reactions, the compliance of patients with multidrug-resistant tuberculosis has always been a difficult problem, and peer education plays a very important role in the compliance of patients with drugs. Yunnan Provincial Tuberculosis Clinical Treatment Center has been trying first. Since 2012, it has started patient-centered care work, recruiting peers to provide online and offline patient compliance support and care services for patients, which has been unanimously recognized by the tuberculosis community at home and abroad. In October 2018, this work was shared at the Union Tuberculosis Hague Conference.

  Research and development of new anti-tuberculosis drugs

  How to Solve the "Last Mile" Problem

  A "street rat" with nowhere to hide (design: Sun Yaping) 

  Nowadays, tuberculosis can be cured. However, the four first-line drugs used for treatment take a long period of time, and conventional treatment takes six months. If you are infected with drug-resistant mycobacterium tuberculosis, it may take years of treatment, and the cost is also very high, which is a common problem facing the whole world.

  "At present, among the 558,000 cases of MDR-TB in the world, only 25% of patients can get treatment for MDR-TB, and the success rate of treatment is only 55%." Dr. Chen Zhongdan, technical officer of HIV/AIDS/viral hepatitis/tuberculosis in the representative office of the World Health Organization in China, said.

  Only Mycobacterium tuberculosis has super drug resistance? Actually, it is not. From the perspective of drug research and development, there are currently four first-line drugs for anti-knot. It is understood that these four drugs are "old drugs" that have been listed since the 1950 s and 1960 s. In the past 70 years, few first-line anti-knotting drugs have entered the public eye. In addition, due to the long treatment cycle, large side effects and heavy economic burden, the treatment compliance is not good. Therefore, it is reasonable for first-line drugs to develop drug resistance.

  Dr. Lu Manchun, Chief Operating Officer of Global Health Drug R&D Center, said that we should realize that if new drugs with the same efficacy as first-line anti-tuberculosis drugs can enter the market and form new treatment schemes, the problem of tuberculosis drug resistance will be greatly alleviated. She further said that in shortening the research and development cycle of new drugs, through innovative technological breakthroughs, such as the artificial intelligence drug design technology developed by the R&D center, the research and development time of new drugs can be greatly shortened, expenses can be reduced and risks can be reduced.

  There is something special about the drugs used to treat tuberculosis. At present, there must be at least three effective drugs in the simplest treatment scheme, and the three drugs need to be used together. Therefore, in the research and development of new drugs, the formulation of the best scheme of combined drug use can not be ignored. Huan Shitong, senior project officer of Bill & Melinda Gates Foundation, said that this is not a study of a drug, and the formulation of a combination drug plan is very important for each drug to enter the market. Once a drug has passed the pre-clinical safety test, it is necessary to consider how to include it in the future combination drug program for evaluation. This will reduce the risk and improve the cure rate of patients.

  In short, on the one hand, we should strengthen and optimize the use of existing tools and methods to accelerate the decline of tuberculosis; On the other hand, in the face of "market failure", it is necessary to increase investment, strengthen all-round research and development, and pay attention to new drugs, vaccines, new prevention methods, and new combined treatment schemes. It is necessary to comprehensively use mechanisms such as financial input, medical insurance, civil support, poverty alleviation and social assistance to reduce the economic burden of patients, so that they can obtain and adhere to high-quality medical services. Only with the participation of the whole society can tuberculosis be better controlled and finally eliminated.

BYD leads the future: the eye of God illuminates the road of new energy.

On February 10, 2025, BYD officially released the national smart driving strategy in Shenzhen, jointly opening a new era of smart driving, and committed to creating a new business card for new energy. The plan takes technological innovation as the vision, upholds the intelligent strategy, and officially launches the "National Intelligent Driving Strategy". Wang Chuanfu, Chairman and President of BYD Group, announced that all models will be equipped with advanced intelligent driving technology, making it possible for all people to drive intelligently, which marks BYD’s breakthrough in intelligent driving and intelligent entry into a new era of new energy.

"Eye of God" intelligent driving system leads innovation

In terms of intelligent driving, BYD has launched three versions based on the latest advanced intelligent driving system "Eye of God": the basic version is called "Eye of God C", the single laser version is called "Eye of God B" and the three laser versions are called "Eye of God A". These three technologies are in the leading position in the industry, bringing remarkable innovation. For example, Eye of God C will be first applied to seagulls on February 10th, 2025. It is equipped with the latest chip, has automatic parking function, and is the most advanced in its class. The collision avoidance speed of AEB is also increased to 100 km/h.. Eye of God B will improve driving safety, and will first release the lane keeping auxiliary function. Eye of God A will be the first to realize the application of urban roads, which will be launched before the end of the year, and based on the world’s first "Eye of God A", a new driving experience will be realized. In the specific technical scheme, BYD’s scheme further enhances the vehicle’s perception ability, making intelligent driving and intelligent parking more reliable and efficient. Through this scheme, BYD not only improves the safety of vehicles, but also brings users a more convenient driving experience. Whether driving at high speed or parking in the city, it can provide all-round support to ensure that every trip is safe and worry-free.

BYD accelerates the process of intelligent driving era.

Entering the era of intelligent driving is of great significance to BYD. As a new energy promoter, BYD will accelerate the intelligent landing and usher in a new growth cycle. On November 18, 2023, BYD released an intelligent solution, officially announcing cooperation with many enterprises to open a new chapter in new energy. At the event site, Han series models led the way, and several models appeared together. In addition, Song LPro+ and Qin PLUS have been listed. Song LPro+ is equipped with the latest operating system and is a high-end intelligent SUV. Qin PLUS is a compact car, and it also launched a number of intelligent functions. The summer series is based on family needs and designed for the whole family, becoming a home MPV. BYD truly realizes a green travel society.

Globalization strategy shows the charm of China’s intellectual creation

Create a smart future and build a new energy brand for the world. BYD relies on strong technical support in the process of globalization. In the past few years, BYD has invested tens of billions of yuan to establish an international R&D team and set up a professional testing team. The company has also obtained a number of international standard certifications and thousands of patents, developed new energy vehicles, and provided millions of users with a green travel experience, successfully achieving the sales target, and at the same time, the operating quality has reached the best in history. Now, with the help of "vehicle intelligence strategy", BYD not only leads the future of new energy, but also shows China Zhizao to the world, and is committed to creating a new business card of global new energy.

Guided by the national intelligent driving strategy, BYD is accelerating the arrival of the intelligent driving era in an all-round way with the "Eye of the Gods" advanced intelligent driving system. With the two-wheel drive of technological innovation and intelligent strategy, BYD not only reshaped the driving experience, but also showed the infinite possibilities and outstanding strength in the new energy field to the whole world in the name of China Zhizao.

Behind the Orient Express, she turned her life into a legend.

Special feature of 1905 film network On November 10th, the latest version was released in domestic cinemas, but this time it was released simultaneously around the world. Domestic audiences can watch this star-studded annual masterpiece at the same time as foreign audiences.

As the representative work of agatha christie, the Orient Express has been remake for the fifth time.

Because the ending is well known, even the poster in this edition is spoiled by itself.

This time, the director and the actor of "Poirot", but the prince of British drama and the successor of laurence olivier, represent the peak of Shakespeare’s performance — — Sir kenneth branagh. 

 

Blana was knighted by Queen Elizabeth II five years ago, so now he should be addressed as Sir.

Blana not only choreographed, directed and acted well on the stage, but also participated in the production of many films. He directed and recently starred in Nolan’s.


In addition to the detective Poirot, the twelve passengers on the new version of Orient Train are also undiscovered talent.The most eye-catching is "Captain Jack"Johnny DeppHe plays the villain in the film. In addition, there are Spanish beauties.Penélope Cruz Sánchez Daisy Ridley, the new heroine of "Star Wars" series, is a professional villain.Willem Dafoe, and the old British play bones.Judi DenchandDerek JacobiWait a minute. It is said that the actors included a total of 76 performance awards.

The Birth of Murder on the Orient Express

The Orient Express has been remake so many times because of its unique charm. It can be called a model of "perfect murder", and the mode of collective crime created by it can be said to be unprecedented in the history of world detective novels.Of course, this story is not made up out of thin air. It all comes from Agatha’s long trip.

 

Agatha in her youth

In 1928, Agatha, who ended her first marriage, sent her daughter to boarding school and bought a boat ticket to Jamaica alone, hoping to go to the West Indies for fun. At the dinner before departure, she got to know Commander Hao and his wife, who had just returned from Baghdad. At their suggestion, Agatha decided to switch to Baghdad and changed her ticket to the Orient Express. This is her first trip alone, and she was trapped in Turkey for six days because of the snowstorm.

The second reason is the sensational Lindbergh kidnapping case in the United States.In 1932, the one-year-old son of flight colonel Lindbergh was kidnapped and blackmailed for $50,000. However, after Lindbergh paid the ransom, the kidnapper brutally tore the ticket.

 

Lindbergh’s one-year-old son

The police suspected that there was a mole in Lindbergh’s house and investigated all the servants. British maids and German gardeners became the main suspects. Under the great pressure of public opinion, both of them chose to commit suicide to clear their suspicions. Two years later, the police arrested hauptmann, a carpenter in new york, and found a large number of gold coupons suspected of ransom in his home. Although hauptmann refused to plead guilty during the trial, he was finally sent to the electric chair.

 

Hauptmann, a kidnapper identified by the police.

Therefore, Agatha used the reaction of all kinds of passengers when she was stranded on the Orient Express, combined with the kidnapping case of Lindbergh, and created the revenge story of twelve "jury members" seeking justice.

Become agatha christie.

So, how did Agatha become the world-famous "queen of detective stories"? In fact, her life is more exciting than her novels, and she even staged a real version. It all started with her first marriage.

Agatha, 22, met handsome but not rich archibald Christie at a dance, and married Archie despite the opposition of her family.

 

Agatha and Archie

After the outbreak of World War I, Archie enlisted as a pilot, and Agatha followed him as a volunteer nurse. She worked in the pharmacy room, dealing with all kinds of drugs, and gradually became a poison expert. This laid the foundation for 83 poisoning cases in her novels later. In the boring work in the pharmacy room, Agatha began to conceive her first detective novel, which was inspired by a Belgian neighbor who fled the war. The great detective Hercule Poirot and his first mysterious affair at styles were born.

 

After the war, Agatha resumed writing detective novels to supplement her family. Her sixth novel, The Mystery of Roger, became a best-selling novel at that time, and the couple finally lived a spare life with a house and a car. But it is easy to share weal and woe with wealth, and the happy days did not last long.

In the same year, Agatha’s mother died, but Archie didn’t give her any comfort because he fell in love with a beautiful young girl, Nancy Nelly. Archie confessed to Agatha and filed for divorce.

At 10 o’clock in the middle of the night on December 3, 1926, Agatha drove out of the door alone. The next morning, people found her car by the lake, and Agatha disappeared!

 

The newspaper of the year

The news of the disappearance of female detective novelists quickly occupied the headlines of major newspapers and even spread to the United States. The police suspected Archie of killing his wife and kept him under close surveillance.

Eleven days later, Agatha, who called herself Mrs. Nelly (please note this surname), was recognized in a hotel two miles from the missing place. When Archie took her home, she looked confused as if she didn’t know her husband at all. Later, the husband and wife announced that Agatha suffered from fragmented memory loss.

 

The newspaper of the year

The accident made Agatha famous. Because of the public’s curiosity about her, her books were sold out of stock. In the following decades, Agatha kept the disappearance a secret and said nothing. Until the end of 1990s, Agatha’s friend Nan’s daughter claimed that her mother Nan and Agatha had planned the whole "script" in order to punish her unfaithful husband. Unexpectedly, it caused an uproar.

This missing drama is exactly the same as the movie Gone Girl.

Agatha divorced Archie two years later, but because of the copyright problem of the novel, she couldn’t change her maiden name, so she had to continue to use her ex-husband’s surname — — Christie.

The story didn’t end, and Agatha finally found her own happiness. Because of the trip to Baghdad mentioned above, Agatha and the archaeologist Wu and his wife became good friends, and through them they met Max Mallowan, 25. Later, she married the archaeologist who was 13 years younger than herself.

 

Max and Agatha

Since then, Max has been accompanied by Agatha on every archaeological trip. These trips inspired the birth of many of her exotic works, including Tragedy on the Nile, appointment with death, Murder in Mesopotamia and They Came to Baghdad and so on.

In her later years, someone asked Agatha if it would be okay to marry a husband so much younger than herself. She said the classic famous saying: "The older I get, the more interesting he will find me." Their love lasted for 45 years until Agatha died peacefully in Max’s arms on January 12, 1976.

Agatha’s routine

Three great masters of world mystery novels

Agatha, arthur conan doyle and Seicho Matsumoto are also called the three great masters of mystery novels in the world. Sir Conan Doyle established the basic model of detective novels and the basic deductive method, while Seicho Matsumoto initiated the social school of mystery novels.Agatha’s greatest contribution is to create the "country villa school", a school of reasoning, and push the "golden age" of detective novels to a peak.

 

The "golden age" of detective stories refers to the emergence of a large number of classical detective writers between the two world wars, except ellery queen and John Dixon Carr, who are also known as the "three masters of the golden age" with Agatha, as well as G.K. chesterton, Dorothy sayers, Margaret allingham and so on. Mysterious affair at styles, the debut of the great detective Poirot, is regarded as the beginning of the golden age.

 

 "Country House School" is a school of reasoning, also known as exclusive case solving.Seemingly calm English countryside or villa mansion, in an almost closed classical environment, a group of people gather together, including nobles, officers, lawyers, doctors, priests and so on. A high-ranking aristocrat is often at the core of various relationships, and he or she may be violent and hated by everyone. Suddenly, he (she) was killed, probably by poison, and everyone around him had criminal motive and suspicion. The incompetent police will consider this case a mystery, and our detective Poirot or Miss Ma Puer will silently observe everyone’s every move. In order to cover up his identity, murderers often kill several more people. Finally, our dear detective solved the mystery, and the murderer must be the most unlikely person. He (she) may be for money, affection, status, or to cover up the secret decades ago.

 

The above reasoning mode is further extreme, and Agatha’s classic has evolved."Blizzard Villa Mode", also known as "Island Mode"A group of people gathered in a mountain villa and were cut off from the outside world because of a snowstorm. Suddenly, one member was killed strangely, and the rest became suspects. Then, in the process of detecting the case, the suspects will die one after another. This model originated from Agatha’s no one lives, and later had a far-reaching impact on the film industry, and even developed an important type of horror film. Kill array in another dimension, cabin in the Woods and other films all use the "blizzard villa model".

In recent years, the fire variety Star Detective is also based on this model.

Because they are too stereotyped, the focus of classical detective novels is to find out who did it, so they are also nicknamed whodunit. However, there is a reason for the formation of such a pattern. The golden age writer represented by Agatha pursues"Ten commandments of mystery novels"They think that detective stories are an intellectual game between writers and readers, just like the popular killing games and werewolf killing. In their mystery novels, there is not much truth, violence and sociality in murder, and all suspects, including murderers, are polite, reflecting the elegance of classical literature. The murderer will be brought to justice, and society will finally regain its balance. So this reasoning is called "Cozy".

Therefore, in this mode, writers focus more on creation."perfect murder"And Agatha’s contribution is that while maintaining the basic pattern, she also challenges the rules. For example, in Murder on the Orient Express, no one stipulates that the murderer can only be one person. Why can’t it be a group of people? Besides, she is very good at confusing readers with narrative tricks. For example, in Roger’s Mystery and The Mouse Trap, the criminal may be the narrator or the detective himself, which breaks the first and sixth commandments of the Ten Commandments of Mystery Novels.

Agatha’s legacy

Agatha is regarded as the best-selling writer in human history. She has written 68 novels, more than 100 short stories, 17 plays, 6 emotional novels published under the pseudonym Mary West mccourt, 1 autobiography and 2 poems. Her books have been translated into more than 103 different languages, with a total sales of more than 2 billion copies, second only to the Bible and Shakespeare. French President Charles de Gaulle and Queen Elizabeth II are her fans.

Agatha has so many works, which one should I start reading? Japanese critics scored all his works and got ten most recommended works:

  1. heavy curtain

  2. Poirot: Five Little Pigs

  3. Marple: Endless Night

  4. A Pocket Full of Rye

  5. Xingfu mask

  6. Poirot: Evil Under The Sun

  7. The Mirror Crack’d From Side to Side

  8. The Passing of Mr. Quin

  9. Poirot: Appointment with Death

  10. password

Agatha’s works are also deeply loved by the film and television circles and have been adapted for more than 180 times.

Among them, the classic ones areBilly WilderDirector,Marlene DietrichStarring

In 1980s, three important Agatha films were introduced into China, and they met the audience in China in the form of translated films, which caused an Agatha fever at that time.

 

Peter UstinovVersion of Poirot, and "The Massacre on the Nile" andEvil Under the Sun.

The last film is the most classic version of Murder on the Orient Express, which was directed by sidney lumet in 1974. Ingrid bergman, who was 60 years old, won the Oscar for Best Supporting Actress for her five-minute long shot in which Poirot interrogated her.

 

In addition to Bergman, there is also the veteran 007 in the film.Sean ConneryandInAnthony Perkins

Finney Poirot

Agatha, who was still alive, attended the film premiere for the first time, and praised Finney for performing her Poirot, although she was still not satisfied with Finney’s beard.

If you want to experience the most authentic Agatha, you can also watch the English drama versions of Detective Poirot and Detective Marple produced by itv. These two series are 4-5 episodes each season, and each episode is 90 minutes independent.

British drama version of Poirot.

The Great Detective Poirot began to be serialized in 1989, and the last episode of the thirteenth season of 2013, Curtain: The Last Case of Poirot, ended with Poirot’s death. david suchet, the leading actor, has always been regarded as the best Poirot actor. He always wears a neat suit, has two signature moustaches, takes off his hat at the sight of people and says "Merci beaucoup, Mademoiselle" in French with Belgian accent (thank you, Miss).

 

The Detective Story of Miss Marple has been serialized since 2004, and the last season is the sixth season released in 2013.

 

Two-term Miss Ma Puer

In the first three seasons, Geraldine Mcewan should be the most vivid Miss Ma Puer, showing this thin and even a little rickety, inquisitive and rambling little old lady vividly. In the last three seasons, Miss Ma Puer was played by Julia McKenzie. Although she was more kind, she was less verbose and nosy.

In recent years, Britain has also produced mini-dramas of no one lives and the prosecution witness, while Japan has produced mini-dramas of Murder on the Orient Express and no one lives, but both of them are relatively ordinary. In the future, Ben Affleck’s "Witness for the Prosecution" (2019) and the American drama version "Miss Marple’s Detective Case" (2020) developed by CBS are under preparation.

In order to see the best Agatha, there is another choice besides the original and the English drama version, that is, the stage play.

In 1946, Agatha wrote a radio play "Three Blind Mice" for the 80th birthday of Queen Mary, England, which was later adapted into a stage play "Mouse Trap", which is still performed in West End of London. Together with "Woman in Black" and "House of Sin", Agatha is called the three famous plays in West End of London.

Stills of the previous stage play no one lives.

Because Agatha’s works have not passed the copyright protection period, the publishing, remake and moving of her works all need authorization. The copyright of Agatha’s plays in China is mainly in the hands of Shanghai Mousetrap Drama Studio. They cooperated with Shanghai Drama Art Center to rehearse plays such as no one lives, Mousetrap and Unexpected Visitors, which are staged in Shanghai all the year round and will also tour Beijing every year.

Friends who can’t see the stage play, let’s come to the cinema to take the luxury train Orient Express, and feel the classical atmosphere of Agatha and the elegant reasoning of the detective Poirot together with a group of acting big coffees. We will leave on November 10th and be there.

All over the world, foreign celebrities are speaking Chinese.

  Recently, South Korean pop star Song Joong Ki sang the Chinese song "Little Lucky" at a meeting in Taipei, and got on the hot search list again with her profound Chinese skills.

  In recent years, when foreign celebrities come to China to attend activities, they never forget to show off a handful of Chinese. From the basic level of "hello" and "thank you" to the master level of barrier-free communication, and then to the great god level of quotations, poems and songs … … When those celebrities started to show Chinese, even the fans were shocked! Let’s see which foreign celebrities have reached Grade 10 in Chinese.

  South Korean President park geun-hye is well versed in China culture, Chinese and China philosophy. In his speech in Tsinghua University in 2013, he repeatedly quoted China’s ancient poems, which made China people feel more cordial.

  For Chinese, Kevin Rudd, the former Australian Prime Minister, can be regarded as "trained". In 1976, Rudd entered the National Australian University, majoring in Chinese and China history. In 2008, Rudd went to Peking University to give a speech, and also made fun of it in standard Chinese: "There is a saying in China called ‘ I’m afraid of heaven and earth, and I’m afraid that foreigners will speak Chinese ’ 。”

  When it comes to foreigners with Grade 10 Chinese, Fukuhara Ai is absolutely committed. Fukuhara Ai, who has a cheerful personality, is deeply loved by the people of China. Her authentic Northeast dialect is enough to make people suspect that this cute "porcelain doll" is my sister in Northeast China.

  Mark zuckerberg, the founder of American social networking site Facebook, is also a well-known China hand, and married his Chinese wife Priscilla Chen in 2012. Mark once gave a speech in Chinese throughout Tsinghua University, and his fluent Chinese surprised everyone.

  Dashan has long been a well-known representative of foreigners in China. In 1984, Dashan began to study China after being admitted to the East Asian Department of the University of Toronto. After graduation, he went to the Chinese Department of Peking University for further study. Later, he learned crosstalk from the famous crosstalk performer Mr. Jiang Kun.

  YANO KO JI, a Japanese artist who is well-known as the host of Hunan Satellite TV’s variety show Everyday, took over many TV series such as Towards the Republic during his stay in China. Through the training of filming and hosting, YANO KO JI’s Chinese level has also made great progress. In 2011, YANO KO JI won the "Best Foreign Artist of 2010" award from Global Times, becoming the first Japanese to win this award. In September 2015, YANO KO JI became the first artist to be commended by the Japanese Foreign Minister for his outstanding contribution to Sino-Japanese friendly relations.

  Lim Yoon A, a Korean actress, has achieved Grade 10 in Chinese, which can be regarded as universally recognized. Pronunciation standard, fluent. When interviewed, I pick up stalks and throw stalks at will, and sometimes I will come to the northeast cavity. I love hot pot and love to string, which perfectly explains the sentence "I can rely on my face, but I have to rely on my talent."

  Abe Tsuyoshi, who is well-known to the audience in China by virtue of his beautiful role in the Japanese drama "Flower Man", is also a master of Chinese. However, Abe Tsuyoshi himself is a Sino-Japanese mixed-race, born in Heilongjiang Province, China, so his fluency in Chinese can be expected. Married China actor Shi Ke in 2009.

  Pei Xiubin, who is well-known to China audiences for The Temptation of Angels and Brilliant Legacy, was recommended by director Wong Kar-wai to enter the Beijing Film Academy for further study. In the 11th episode of "The Temptation of Angels", Pei Xiubin conducted business talks in fluent Chinese, which surprised the audience in China and was called "the best Chinese artist in South Korea".

  GACKT, the Japanese "glamorous devil", is a full-fledged individualist musician, who knows four foreign languages, including French, Chinese, Korean and English. In the variety show "Don Ben Brothers", he once talked with Bidai Syulan in Chinese, and the standard of pronunciation is staggering.

  Li Duohai, a Korean actress, insisted on answering questions in Chinese all the time when she was interviewed and recorded in China, without any pressure. In fact, as early as 2005, in the Korean drama My Girl, Li Duohai began to speak Chinese in the first episode, translating for China guests, and his articulation was clear, which was amazing.

Summary of more than 130 new cars launched/listed at Beijing Auto Show

W3 hall

Starting a new car: Nezha V.

  At the 2020 Beijing Auto Show, Nezha V, the third production car of Nezha Automobile, was officially released. The new car is positioned in a small SUV, and the whole car adopts the brand family design language. The NEDC has a comprehensive working life of 401km and will be listed in the fourth quarter of 2020.

Home of the car

Home of the car

  In terms of appearance, Nezha V continues the family-style design of Nezha automobile, and the lines of the whole vehicle are smooth. The completely closed front face shows its identity as a pure electric vehicle. The design of connecting the headlight group with the waistline of the car body is novel, and the proportion of the whole car is coordinated. The application of red trim has played a good role in embellishing the rejuvenation of the whole vehicle.

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Home of the car

  In terms of body size, Nezha V is a small SUV with a length, width and height of 4070mm×1690mm×1540mm and a wheelbase of 2420mm respectively. The rim is blade-shaped, which is quite dynamic and harmonious.

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  As for the interior, the layout of the center console of Nezha V is quite simple. The traditional instrument panel has been moved to the front of the center console, while the central control screen has a vertical layout with a size of 13.3 inches. There are almost no physical buttons in the central control part, and all operations need to be realized through the central control screen. Nine wake-up-free AI intelligent voices can realize real-time online of AI partners, and have built-in long and short video apps from bilibili and Tik Tok, remote control of the whole scene, smart home interconnection of Mijia and other scene interactions. It can realize advanced early warning automatic driving assistance.

  Nezha V is also equipped with a number of intelligent safety configurations, which can realize advanced early warning automatic driving assistance, including collision warning (FCW), traffic signal light recognition (TLR), vehicle start warning (SGW), pedestrian collision warning (PCW), lane departure warning (LDW), intelligent driving recorder (DVR) and traffic sign recognition (TSR).

Home of the car

  Nezha V positioning small pure electric SUV, with length, width and height of 4070mm×1690mm×1540mm and wheelbase of 2420mm, uses Contemporary Amperex Technology Co., Limited battery, and NEDC has a battery life of 401 km under comprehensive working conditions.


Starting: Nezha Eureka 03 concept car

  At the 2020 Beijing Auto Show, Nezha Eureka 03 concept car made its debut. The new car continues the smooth lines of Nezha cars in styling and is positioned as a coupe. Although the concept car may not be mass-produced in the end, it can be judged that Nezha Automobile will definitely have plans for car products in the future.

Home of the car

Home of the car

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  As a concept car, the new car as a whole exudes a strong sense of the future. The closed front face shape is consistent with the electric vehicle manufacturing brand Nezha. The arc from the roof to the tail is smooth, similar to the hatchback. The horizontal penetrating strip taillights are very characteristic. I wonder if they can be retained in future production models.

Home of the car

  The new car also uses many innovative technologies. For example, using a whole piece of complete curved surface screen, the effect presented on Eureka 03 is that the A-pillar is almost completely covered by the screen, and the look and feel is more complete and tidy. CMS electronic rearview mirror system will replace the traditional rearview mirror, integrate blind spot detection function, and provide timely warning through "transparent" A-pillar to protect users’ driving safety to the greatest extent.

  Through the five millimeter-wave radars and six high-definition cameras equipped by the vehicle itself, the obstacles and vehicles around the vehicle in 360 degrees can be monitored in real time when driving on the expressway. Under the condition of ensuring safety, the lane can be changed independently without manual control. In a limited scene, a high-precision map of the route from the saved parking space to the fixed point. The vehicle can complete the parking work from the fixed point to the parking space by itself without the driver.

  Eureka 03 has a length, width and height of 4800mmX2000mmX1400mm and a wheelbase of 2900 mm. It has a battery life of 800 kilometers, an acceleration of 100 kilometers in less than 4 seconds, and L4-class conditional automatic driving technology, showing the intelligent safety technical strength of Nezha cars.


Listing: Land Rover Range Rover 50th Anniversary Limited Edition

  Jaguar Land Rover officially released the 50th anniversary edition of Range Rover at Beijing Auto Show to commemorate the first generation of Range Rover in 1970. The car offers seven special body colors, with a limited sale of 1,970 vehicles worldwide, while China has a quota of 400 vehicles.The price is 2,025,800 yuan..

  In terms of appearance, the overall shape of the new car is not much different from the ordinary version, but the details have been adjusted to highlight the special identity of the car. For example, the new car has added the "Fifty" logo under the side fender and at the rear of the car body; At the same time, in order to restore the classics, the new car has specially adjusted the three colors of car paint "Bahama Gold", "Davos White" and "Tuscan Blue" which are the same as those of the first generation Range Rover. This is the first time that Land Rover has introduced classic replica car paint colors on limited edition models in 35 years. In addition, the new car also has four special body colors with great collection value, namely "Santorini Black", "Aruba Silver", "Carpathian Grey" and "Rosello Red".

Land Rover (Imported) Range Rover 2020 50th Anniversary Edition

  In terms of interior, the new car is wrapped in leather in many places, plus a full LCD instrument panel, a four-position multi-function steering wheel and a central embedded multimedia touch screen, which makes the new car full of texture. The new car also highlights the identity of the 50th anniversary edition of the new car through detailed design, such as adding the "Fifty" logo to the headrest, center console, welcome pedal and other details.

Land Rover (Imported) Range Rover 2020 50th Anniversary Edition

  In addition, the new car covers long/short axle, gasoline/diesel and hybrid vehicles, but the official has not made it clear what kind of power the new car will carry. For reference, the Range Rover on sale in China is divided into 3.0T inline six-cylinder engine +48V light hybrid version, 5.0T eight-cylinder supercharged engine version and 2.0T plug-in hybrid version. Among them, the maximum power of the 3.0T low-power engine can reach 360 horsepower and the maximum torque is 495N·m;; The high-power version has a maximum power of 400 HP and a maximum torque of 550 N m.. The 5.0T version has a maximum power of 565 HP and a maximum torque of 700 N m.. The comprehensive power of the 2.0T plug-in hybrid version is 404 horsepower, and the comprehensive torque of the system is 640 N m.. The above power versions are all matched with the 8-speed automatic manual transmission.


Starting: Land Rover Discovery Sports PHEV

  At the 2020 Beijing Auto Show, Land Rover brought its Discovery Sport PHEV model, and the new car will be equipped with a plug-in hybrid power system consisting of a 1.5T three-cylinder engine and an electric motor.

  In terms of appearance, the new car basically continues the styling design of the fuel version of the car for sale, but slightly adjusts some details. The air inlets of the fog lights on both sides under the front grille are designed as C-shaped, and the charging sockets of the new car are set at the right front fender of the vehicle. In terms of body size, its length, width and height are 4597/1904/1727mm and its wheelbase is 2741 mm.

  The rear of the car is basically the same as the ordinary version. The overall visual center of gravity of the rear is higher, and the style of the taillights is more complicated. The design of the rectangular exhaust pipe at the bottom is only for decoration. In addition, the "P300e" logo is added to the rear of the car, which is one of the few places where the appearance can show its new energy identity.

  The interior adopts Land Rover’s classic family-style design language, which reveals exquisiteness in luxury. The style of the steering wheel is the same as that of the Range Rover Sport Edition. The size of the full LCD instrument is 12.3 inches, and the internal display interface has been adjusted accordingly.

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Home of the car

  In terms of power, the car will be equipped with a plug-in hybrid power system consisting of a 1.5T three-cylinder engine and an electric motor. Among them, the maximum power of the 1.5T engine is 200 HP, which meets the national VI emission. The maximum power of the motor is 109 horsepower. The comprehensive power of the new car is 309 HP and the maximum torque is 540 Nm. The transmission is matched with an 8-speed automatic manual transmission, and the ternary lithium battery is provided by Contemporary Amperex Technology Co., Limited. Under NEDC working conditions, the pure battery life is 62km, and the new car can realize 0-80% charging in just 30 minutes.


Starting: WEY Tank 300 Special Edition

  The 2020 Beijing Auto Show officially opened, and WEY brought a real car with a special edition of Tank 300 at this auto show. The new car is based on the regular version of Tank 300, but the appearance adopts a more sporty off-road kit. In addition, the interior of the tank 300 was announced at the press conference, and it was indicated that it would be officially launched and delivered in December. In the future, tank models will also launch a 3.0T+9AT powertrain.

Home of the car

Home of the car

  In terms of appearance, the new car adopts a new design language, which is very tough and atmospheric as a whole. Specifically, the new car adopts a rectangular front grille with rounded corners, and the interior is supplemented by a round retro LED headlight group and a three-frame front grille, which not only enhances the integrity, but also fits the rough design style of the hard-core SUV. At the same time, its front face is almost vertical, which further increases the sense of strength of the car with the raised lines above the hood.

Home of the car

  In terms of interior, the interior design concept of the new car follows the hard-core off-road style, with large-area square straight contour lines and rounded chamfers. In addition, the round air conditioning outlet and round function knob are matched with square diamond stitching interior panels, which makes them more textured. At the same time, the integrated screen composed of double 12.3-inch full LCD instruments and central control LCD screen ingeniously enhances the sense of science and technology of the car.

  In general, the new car adopts a square box body design as a whole, which is very similar to many hard-core off-road SUVs. The hinge on its right side also indicates that it will adopt a horizontal tailgate, and the vertical door handle on the left side of the tailgate also highlights the car’s personality style in detail. In addition, it is more distinctive that its license plate frame does not appear in the center, but is located in the left position.

  In terms of power, the new car will adopt front double wishbone independent suspension/rear integral bridge dependent suspension and non-loaded body design, so we speculate that the new car will use longitudinal engine layout. We will continue to pay attention to more information about power and new cars.


Starting: WEY VV5 Yuanqi Orange Edition

  At the WEY booth of this auto show, the 2021 VV5 specially designed for young people ushered in the debut of the original orange model. It is expected to be listed this year.

Home of the car

  The 2021 VV5 is an SUV with high-order intelligent driving interest built by WEY brand for the new generation, which was just launched on September 20th. VV5 Yuanqi Orange uses global fashion elements to empower the body design.

Home of the car

Home of the car

Home of the car

  In terms of appearance, the new model maintains the outline and style of the old model. For example, the air intake grille still maintains a polygonal shape, and chrome decoration is used inside the grille to make it more three-dimensional. The left and right sides of the front enclosure bottom have a strong sense of quantity, and the visual effect is enhanced by chrome decoration.

Home of the car

  The interior has not changed much, and the center console is designed slightly to the driver’s side, which is convenient for driving. Both the instrument panel and the center console screen are 12.3 inches, which have good performance in display effect and clarity. The appearance and interior are blessed with exclusive orange, and the brand-new 19-inch Michelin tires with luxury perception bring the most cutting-edge visual trends to young consumers.

Home of the car

  Moreover, in terms of improving intelligent technology, VV5 Yuanqi Orange is even more indispensable, and it is added again on the basis of the extremely high original configuration rate. Through six intelligent driving items, such as front anti-collision radar, parallel assistance, lateral warning of reversing, lateral braking of reversing, early warning of opening doors and early warning of rear collision, and the standard of three-view DVR driving recorder, it shows a more interesting side, so that young car owners can enjoy the "eye-catching ceremony" of pedestrians and get VV5 more.

  In terms of power, the new car is consistent with the regular version. The 2021 VVV 51.5 T and 2.0T turbocharged engines have the maximum power of 171 HP and 227 HP, and the maximum torque of 287 Nm and 387 Nm, respectively, and meet the national six emission standards. In terms of transmission system, all new cars are matched with wet 7-speed dual-clutch gearbox, and the 2.0T model will also be equipped with four-wheel drive system. The official 0-100km/h acceleration time is 6.6 seconds.


Starting: Volvo XC40 RECHARGE

  During the 2020 Beijing Auto Show, the Volvo XC40 RECHARGE was officially unveiled and opened for blind subscription. As the company’s first pure electric vehicle, the release of this car officially started the first shot of Volvo brand electrification offensive. It is reported that this car will be sold in a brand-new factory direct mode, and this is also an excellent exploration of Volvo’s future car sales model.

  From the appearance, the Volvo XC40 RECHARGE continues the design style of the fuel version. The difference is that this car adopts a closed air intake grille with a lower air intake design, which not only highlights the identity of a pure electric vehicle, but also creates a simple feeling for the front face of the whole vehicle. The new car still adopts the family-style headlight design of "Raytheon Hammer", and the Nordic style is obvious.

  From the side shape, the Volvo XC40 RECHARGE, which was unveiled this time, adopts a two-color body design with a white body and a blackened roof, which is more energetic. Like the fuel version, the new car outlines a good sense of light and shadow with quite complicated lines; The difference is that the new car has a charging port at the front and rear parts on the left. In the rear design, the new car has distinct layers, and adopts the "boomerang" taillight, which looks full of vitality. At the same time, in order to enhance the sense of movement of the whole car, the new car has also designed a "fake exhaust" decoration at the rear.

  

  In terms of body size, the length, width and height of the new car are 4425/1863/1651mm and the wheelbase is 2702mm respectively. In terms of power, Volvo XC40 RECHARGE is equipped with ternary lithium-ion battery provided by Asia-Europe Automobile Manufacturing (Taizhou) Co., Ltd., and the motor is provided by Valeo, with a maximum power of 204 HP and four-wheel drive. Referring to the trailer, Volvo pure electric vehicles will adopt the naming rule of P+X to distinguish fuel vehicles.

Since 83,800, JAC Ruifeng M3 1.5T National Sixth Edition has been listed.

  [car home new car listed] A few days ago, we learned that (|) 1.5T national version 6 was listed.The price range is 83,800-94,800 yuan.. The main change of the new car is to upgrade the 1.5T version from National Five to National Six.

Guide Price of Ruifeng M3 New Model car make and model Price (ten thousand yuan) Ruifeng M3 IKEA High Power Edition 1.5T 5MT Luxury 8.38 Ruifeng M3 IKEA High Power Edition 1.5T 5MT Luxury Intelligent 8.88 Ruifeng M3 PLUS IKEA High Power Edition 1.5T 5MT Luxury 7-seat 9.28 Ruifeng M3 PLUS IKEA High Power Edition 1.5T 5MT Luxury 9 Block 9.48

Jianghuai Automobile Ruifeng M3 2021 PLUS IKEA High Power Edition 1.5T Luxury 9-seat

  The models listed this time are all equipped with HFC 4B2-4E1.5t engines, and the emission standards meet the requirements of National VI. At the same time, the maximum power of the engine has increased from 108kW to 110kW, that is, from 147 HP to 150 HP. The peak torque has not been adjusted, and it is still 210 Nm.

Jianghuai Automobile Ruifeng M3 2019 Maker Edition 1.8L Luxury Intelligent

  As a new model, the configuration of the new car is also different from the existing national six models. For example, Ruifeng M3 1.5T 5MT IKEA high-power luxury model is different from some existing models in details such as automatic headlights, seat fabrics and air conditioning.

Editor’s comment:

  After the 1.8L version was upgraded to National Sixth, the 1.5T version of Ruifeng M3 was also upgraded to National Sixth, and the launch of the new car will continue to enrich the selectivity of this car. (Text/car home Chen Hao)

Seize guns and electric detonators! The express parcel is hidden, and the police have cracked the gun case.

       CCTV News:Recently, the police in Erdos, Inner Mongolia, announced that they had cracked a series of cases of illegally buying, selling, holding and manufacturing guns supervised by the Ministry of Public Security, and arrested 12 suspects, 20 guns of various types, nail bullets, electric detonators for initiation and gun-making tools.

       On March 1st this year, a parcel caught the police’s attention when the public security police of kangbashi Public Security Bureau of Ordos City, Inner Mongolia routinely inspected the delivery enterprise.

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       Qiao Peijun, a policeman from Habaghi Police Station of kangbashi Branch of Ordos Public Security Bureau, said: "A paper box with no logo on it. A gun sight with a length of 140 mm scanned by an X-ray machine. "

       According to this clue, the police arranged a visit and quickly locked Chen Mou in Dongsheng District of Ordos City. On March 3rd, the police searched Chen Mou’s residence according to law and seized a small caliber rifle. According to Chen Mou, he has a total of three guns, except this small-caliber rifle, and the other two were given to his classmate Yang.

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       Zhang Lei, instructor of Habaghi Police Station of kangbashi Branch of Ordos City Public Security Bureau, said: "A single-barrel shotgun and a double-barrel shotgun are standard guns, and their lethality is relatively large. After seeing them, his classmates said that they would turn over these two guns for Chen Mou, and then as for not turning them over, Chen Mou finally didn’t ask."

       In view of the seriousness of the case, the police set up a task force. On March 5, Yang was arrested and a single-barrel shotgun and a double-barrel shotgun were searched from Yang’s home. Yang confessed that there are also Mu and Ba who illegally hold guns. Subsequently, the task force arrested Mu and Ba, and seized a small caliber rifle in Mu’s home.

       Qiao Peijun, a policeman from Habaghi Police Station of kangbashi Branch of Ordos City Public Security Bureau: "After the trial of Ba, one of the two shotguns in Yang’s hand, a single-barrel shotgun powered by gunpowder, was sold to Yang by Ba, and his behavior has violated Article 125 of the Criminal Law, which constitutes the crime of illegally buying and selling guns and ammunition."

       After continued investigation, five suspects involved in the case were arrested and five guns of various types were seized.

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       After the five suspects were arrested, Ordos police followed the trail and conducted an in-depth inspection of the delivery enterprises of logistics companies, and arrested seven suspects involved in gun cases.

       On March 5th, the police of kangbashi Branch of Public Security Bureau of Erdos City, Inner Mongolia, while combing the information of local delivery enterprises, verified that a tubular parcel sent from other provinces was suspected of being involved in guns.

       Qiao Peijun, a policeman from Habaghi Police Station of kangbashi Branch of Ordos Public Security Bureau, said: "The document says a clothes rack, but it is actually a tube, and it is found to be a seamless alloy steel pipe with a diameter of 6.5. Gun experts told us that this is a spare part of a gun. "

       Through the analysis and judgment of the mobile phone information of the suspect Yang, the task force targeted a person named Yang Moha in Ejinhoro Banner.

       Qiao Peijun, a policeman from Habaghi Police Station of kangbashi Branch of Ordos Public Security Bureau, said: "We summoned Yang according to law. Yang Moumou refused to confess his gun-related behavior. Later, in the face of the situation we had, Yang Moumou had to admit that the seamless alloy steel pipe he bought was handed over to his friend Bumou, who made guns for him. "

       On March 11th, the task force arrested Bumou, and seized 2 power guns, a set of gun tools, 10 electric detonators for initiation and several gun-making parts on the spot. On March 12, the police seized three power guns in another residence of Bumou.

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       According to the account of the criminal suspect Bumou, the police arrested his accomplices Damou and Shimou and their downline Amou, Ganmou and Simou. From the homes of these suspects, the police seized 10 guns of various types, gun-making tools, semi-finished guns, nail bullets, steel balls and electric detonators for initiation.

       After identification, these guns are all lethal guns. The police reminded that our country’s laws prohibit any individual from illegally holding or hiding guns and ammunition, and no one should take any chances.

       Qiao Peijun, a policeman from Habaghi Police Station of kangbashi Branch of Ordos Public Security Bureau, said: "Most of the guns seized in this case were used for hunting. Here, we remind the broad masses of the people that illegal manufacturing, trading, transportation, mailing and storage of guns, ammunition and explosives are legally responsible. "

       At present, the case is under further investigation.

Musk’s "slimming medicine" made this European pharmaceutical company "rich as an enemy"

  With Wegovy, regarded by many as a "miracle drug for losing weight", selling well in the United States, Danish pharmaceutical giant NovoNordisk has become the second largest company in Europe after French luxury goods giant LVMH in one fell swoop, making well-known Danish companies such as Lego and Carlsberg "put to shame".

  ▲ Novo Nordisk "slimming medicine" Wegovy

  For Denmark, with a population of only 5.8 million, Novo Nordisk has now become a "rich as an enemy" behemoth, and in 2022, Denmark’s annual GDP will not be equal to the market value of this company. The director of the Bank of Denmark admitted that because Novo Nordisk’s export scale was too large, Denmark had to deliberately lower the domestic benchmark interest rate to maintain the exchange rate balance with the euro.

  The Danish economist Rasmussen wrote an article reminding that although Danish families who have repaid their mortgages are very happy with the policy of low interest rates, it is not a good thing for small countries to rely too much on a certain enterprise. For example, he said that the Finnish economy was highly bound to the fate of Nokia, and Finland’s economic development was seriously dragged down by Nokia after the rise of iPhone.

  Musk "brings goods"

  Novo Nordisk’s sales revenue increased greatly.

  In October 2022, Tesla founder Musk replied to netizens on Twitter, saying that he lost weight crazily within one month and achieved the effect visible to the naked eye, and his secret was to regularly fast food and Wegovy.

  The "Wegovy" mentioned by Musk is the trade name of the slimming drug "Smegrupeptide" developed by Danish pharmaceutical company Novo Nordisk. In June 2021, the drug was approved for marketing by the US Food and Drug Administration (FDA). In the same year, this drug was approved for the treatment of type 2 diabetes in China mainland market, but so far this drug has not been approved for weight loss indications (that is, it cannot be used as a weight loss drug).

  The drug is well known to the public because of Musk’s "bringing goods" and the use of it by some European and American rich people in the fields of finance, science and technology to lose weight, which has also caused the sales of Wegovy to soar, and even Ozempic, a sister product of Novo Nordisk (Chinese name "Novo Thai"), is out of stock globally due to its hot sale. Searching for "Wegovy" and "Ozempic" on overseas social platforms, there are a lot of videos to promote their weight loss effect, and the related tags have accumulated hundreds of millions of views.

  On August 10th, Novo Nordisk reported in its semi-annual report that its sales increased by 30% and its operating profit increased by 32% in the first half of this year at constant exchange rate. Thanks to the market interest in Wegovy, its diabetes and obesity departments performed particularly well. In the North American market, the company’s sales of diet pills increased by 46%.

  Lars Joergensen, President and CEO of Novo Nordisk, said in a statement: "The sales growth is due to the increasing market demand for diabetes and obesity treatment, and our company serves more patients than ever before. The performance in the first six months has enabled us to improve our expectations for the whole year. "

  Director of Danish Bank:

  The hot sale of "slimming medicine" affects the interest rate decision

  In the booming sales situation, Novo Nordisk’s share price rose by 73% this year, becoming the second largest company in Europe, and its market value is second only to that of French luxury goods giant LVMH.

  Based on the latest closing price, the market value of Novo Nordisk is about US$ 417.8 billion (about RMB 3.05 trillion). Last year, Denmark’s GDP totaled 398.3 billion US dollars (about 2.9 trillion yuan), which was still less than the market value of a company of Novo Nordisk. Because Novo Nordisk has brought huge export income to Denmark, Denmark even had to lower interest rates and increase foreign exchange reserves to deliberately weaken the competitiveness of its currency.

  Jens Petersen, director of the Bank of Denmark, said helplessly: "It sounds like a joke to say that the American weight loss craze has affected Denmark’s benchmark interest rate, but in fact it is true."

  ▲ Danish scenery

  On August 16th, local time, the report issued by the Bank of Denmark said, "We have seen the growing role of the pharmaceutical industry in the Danish economy, which has put pressure on the currency exchange rate and the national policy interest rate, and there is a real connection between them."

  At present, Denmark’s monetary policy is linked to the euro, so the country’s central bank fine-tunes its monetary policy through money market intervention and interest rate adjustment, so as to keep the exchange rate of Danish krona stable against the euro. Due to the explosive growth of Novo Nordisk’s performance, foreign businessmen rushed to buy Danish krone to buy popular drugs such as Wegovy, and the trend of Danish krone has been very strong compared with the euro.

  In order to keep the exchange rate balanced, the Danish monetary authorities must deliberately weaken the competitiveness of the krona, so they cut Denmark’s benchmark interest rate to a level lower than the euro zone interest rate. According to the report of the Bank of Denmark, due to the continuous strengthening of pharmaceutical exports, Denmark may be forced to expand the interest rate difference to more than 40 basis points, and at the same time, Denmark will increase foreign exchange reserves such as the euro.

  Sydbank, another bank, estimates that since the end of 2021, the pharmaceutical industry has increased Denmark’s GDP by nearly 2%. The bank is worried that the "outshine others" of the pharmaceutical industry may cover up the weaknesses of the Danish economy in other fields.

  Economist:

  Finland and Nokia are "lessons from the past"

  Danish economist Sinus Rasmussen wrote that although Novo Nordisk’s success has created employment opportunities and local investment in Denmark, and Denmark’s low interest rate policy has also benefited families who have repaid their mortgages, he still reminds Danes that the lifeline of the national economy should not be tied to one company.

  Rasmussen said: "For small countries, it is risky to let a domestic company play such a disproportionate role in the economy. Many years ago, Finland’s economy was dominated by telecom giant Nokia. At its peak in 2000, the company’s revenue accounted for 4% of Finland’s GDP, more than one-fifth of its exports and 70% of the national stock value. It played an important role in Finland’s growth from 1995 to 2007. During that time, Finland’s per capita GDP increased by 55%, almost twice the growth rate of the United States. "

  However, the decline of Nokia also coincides with Finland’s economic stagnation track after the 2008 financial crisis. Some analysts pointed out that because the iPhone launched by Apple brought about tremendous changes in the mobile phone market, the collapse of Nokia in the mobile phone market aggravated Finland’s economic difficulties. Under the influence of austerity policies and the involvement of the euro zone crisis, Finland’s national per capita income continued to decline in the next decade.

  Red Star journalist Zheng Zhi

Manual transmission and automatic transmission: the game between driving pleasure and practicality

Manual transmission and automatic transmission: the game between driving pleasure and practicality

Today in 2024, with the continuous progress of automobile technology and the change of consumer preferences, the choice between manual transmission and automatic transmission has become the first important decision faced by many prospective drivers. This choice is not only related to the learning of driving skills, but also to the expectation and adaptation of future car use scenarios.

From the data point of view, the global market share of manual transmission models is declining year by year. In China, in 2020, manual transmission still occupied 10.7% of the market share, but by 2021 it had dropped to 7.2%, and now it is less than 4%. The market share of manual transmission models in the United States and Japan is only 1% and 2% respectively. This trend reflects that with the intensification of urban traffic congestion and consumers’ pursuit of driving convenience, automatic transmission models are more popular because of their simple operation and easy to use.

Manual gear:

Advantages: high speed, good hand feeling, fuel saving, low maintenance cost and relatively cheap car price. For those who love driving, manual gear provides more driving pleasure and participation, and can shift gears according to the speed and engine sound in time to realize the driving experience of people and vehicles.

Disadvantages: In the urban congestion environment, frequent operation of clutch, gear, throttle and brake not only increases the driver’s physical burden, but also reduces the driving efficiency. For beginners, the learning cost of manual gear is high, and it may be more likely to cause tension and psychological pressure in urban driving.

Automatic gear:

Advantages: simple operation, especially suitable for driving in urban congestion environment, reducing the physical burden and psychological pressure of drivers. For novices, automatic transmission models are easier to use and reduce driving difficulty.

Disadvantages: Compared with manual transmission, automatic transmission models may have higher fuel consumption and maintenance costs, and may lack driving pleasure in some cases. Some drivers may feel that the throttle response of automatic transmission is too tight, which is not as light as manual transmission.

From the practical point of view, automatic transmission models are undoubtedly the mainstream choice in the current market. With the intensification of urban traffic congestion and the acceleration of people’s life rhythm, the convenience and comfort provided by automatic transmission models are more in line with the needs of modern consumers. However, from the perspective of driving pleasure and skill improvement, manual transmission models still have irreplaceable value. For those who love driving and pursue the experience of integrating people and vehicles, manual transmission models provide more possibilities and challenges.

The existence of manual transmission models is also of certain significance to the diversity of automobile technology and market competition. Although automatic transmission technologies such as dual clutch are developing continuously, manual transmission models still maintain a certain market share in some specific fields and consumer groups. This is not only the inheritance of traditional driving skills, but also the respect for the diversity of automobile technology.

To sum up, the choice of manual transmission and automatic transmission should be decided according to the individual’s driving needs, skill level and preference. For those who pursue driving pleasure, like challenges and sense of control, manual transmission is undoubtedly a better choice. For those who pay attention to driving convenience, comfort and efficiency, automatic transmission models are more suitable. In the future, with the continuous progress of automobile technology and the change of consumer preferences, the game between manual transmission and automatic transmission will continue to exist, and each will occupy a place in the market. Therefore, whether you choose manual transmission or automatic transmission, you should make a wise decision based on your actual situation and needs.

Lin Jiaxin left pain Huang Lei right love Fan Wei.


Lin Jiaxin (right) and Ku Kui Kei went to Guangzhou to interact with the audience.


  (Reporter Wang Zhenguo/Wen Wangweixuan/Photo) The comedy "Love Call Transfer 2", which will be released on the 28th of this month, was held in Guangzhou the night before. Director Zhang Jianya and starring Lin Jiaxin and Ku Kui Kei were present to interact with the audience. However, Lin Jiaxin and Ku Kui Kei lacked tacit understanding.


  Ku Kui Kei:


  Chasing girls is singing in her ear.


  Nie Bing, a girl played by Lin Jiaxin in Love Call Transfer 2, won 12 dating opportunities given to her by angels, and then met 12 men of different types and occupations, among whom Ku Kui Kei played an insurance salesman. At the press conference held on the evening of 17th, Ku Kui Kei blew herself up about her early love, saying that she had also used the girl-chasing bridge like "singing in her girlfriend’s ear" in the film: "I didn’t enter the business at that time, so I sang the songs of my predecessors. At that time, it was at the seaside in Tsim Sha Tsui, Hong Kong. Wow, now I think it is very romantic. She is in my arms and my ear is on my mouth. I will sing it to her. "


  However, when Ku Kui Kei was filming, he was busy promoting the music album, so he only spent 40 hours in the group shooting, and he didn’t know some key plots in the film. On the evening of 17th, when he was asked the question "What dish did the insurance salesman do that touched Nie Bing", Ku Kui Kei was embarrassed, and answered three answers "Mom’s rice", "Mom’s food" and "Mom’s shrimp" in succession, but Lin Jiaxin, who knew the answer, just smiled at the side without any tacit help. Director Zhang Jianya quickly cleared the way: "This is not his fault, filming the scene of Lin Jiaxin eating food.


  Lin Jiaxin:


  You can’t accept sibling love in your life.


  Love Call Transfer 2 is Lin Jiaxin’s first mainland film, and it is also a comedy route that she seldom tries. Lin Jiaxin said that she played this role in a "silly girl" way: "I really seldom try comedy, but I know that I have to catch a few points-Pisces, a girl who is about to turn 30, and a TV presenter, so I think I should catch’ silly’ because girls’ stupidity is very cute. I don’t want to pretend to know comedy very well. I hope to perform the role of Nie Bing with silly feelings. "


  When it comes to the actor who feels the best in the film, Lin Jiaxin didn’t say it was Ku Kui Kei who was standing by, but Huang Lei who played the painter in the film, but she didn’t forget to add: "Of course, it feels good with Ku Kui Kei." Later, Lin Jiaxin explained, "Some people can’t establish too many tacit understandings because the shooting time for each of them is only two or three days.". What impressed me more was Huang Lei. There was a scene where I broke up with Huang Lei. He was crying, and I was suddenly tempted. I was infected in an instant and wanted to hurt him. "


  I talked about 12 boyfriends in the movie. What kind of boyfriends does Lin Jiaxin like in life? Lin Jiaxin said, "I can’t accept sibling love, and I prefer mature men. The teacher Fan Wei in the film is not bad, very cute, and her eyes are always smiling, so she has no trouble with him. In real life, I will choose mature and humorous people. "


  Reporters watch movies:


  Audience favorite


  Fan Wei is funny.


  At present, Fan Wei, Huang Lei and Deng Chao are the three leading actors in Love Call Transfer 2. Talking about the comparison of the length of the actor’s scenes in future films, director Zhang Jianya said: "The film was three hours long when it was roughly cut, and many good scenes were cut off due to the limitation of the film length."


  According to the reporter’s statistics, among the films, Fan Wei took on the most funny lines, and his performance also got the most laughter. He plays Fan Zhongju in the film. He owns a huge sum of money and a famous car. He is a veritable tycoon. Based on the life principle of "a vast sea of people, weeds everywhere, why not look for flowers", he has a crush on Lin Jiaxin. When Lin Jiaxin said that he liked Prince Charming, Fan Wei looked embarrassed: "That’s bad, they all call me a dark horse fat man."


  Alec Su, an idol student, also performed brilliantly. He played an almost crazy draft player in this film. He participated in all kinds of draft programs, including "Good Man", "Fast Man", "Real Man" and "Handsome Man", in order to show a small face in front of the camera, and he also paid bribes to all kinds of people in the cast for the sole purpose of being famous. In the film, Alec Su not only boasts the "Xu Wenqiang" of Shanghai Beach, but also sticks his head out of the sky window affectionately in Lin Jiaxin’s car, waving to the roadside frequently and shouting "Hello friends at the top of the mountain". Before the words are finished, a garbage bag blows and sticks it on Alec Su’s face.


  (Wang Zhenguo)

Editor: Zhang Renhe